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超声检查中应用 2.5g/kg 右美托咪定滴鼻的临床效果及安全性分析。

Clinical Effect and Safety Analysis of 2.5 g/kg DEX Nasal Drop in Child Undergoing Ultrasound Examination.

机构信息

The Department of Anesthesiology, Children's Hospital of Zhejiang University School of Medicine, Hangzhou 310051, China.

The Department of Anesthesiology, the First Affiliated Hospital of Wenzhou Medical University, Wenzhou 325099, China.

出版信息

J Healthc Eng. 2022 Apr 12;2022:3486313. doi: 10.1155/2022/3486313. eCollection 2022.

Abstract

In order to meta-analyze the clinical effect and safety of dexmedetomidine (DEX) intranasal sedation in child ultrasound examination, literature retrieval is carried out in Wanfang Medicine, PubMed database, domestic medical research journals. The relevant medical information literature on clinical effects and safety are analyzed by using Rev Man 5.2 software. The retrieved literature is screened according to the research object, method, disease type and other criteria. The results of meta-analysis show that dexmedetomidine intranasal sedation is applied to child undergoing ultrasound examination, and the SPO2 and sedation time are significantly higher than those in the conventional sedation group ( < 0.05). The time/score is significantly lower than that in the conventional sedation group ( < 0.05), and the incidence of adverse reactions in the dexmedetomidine intranasal sedation group is significantly lower than that in the conventional sedation group ( < 0.05).

摘要

为了荟萃分析右美托咪定(DEX)经鼻镇静在儿童超声检查中的临床效果和安全性,在万方医学网、PubMed 数据库、国内医学研究期刊中进行文献检索,使用 Rev Man 5.2 软件对临床效果和安全性相关的医学信息文献进行分析。根据研究对象、方法、疾病类型等标准对检索文献进行筛选。荟萃分析结果显示,右美托咪定经鼻镇静应用于行超声检查的儿童,其 SPO2 和镇静时间均显著高于常规镇静组( < 0.05),时间/评分显著低于常规镇静组( < 0.05),且右美托咪定经鼻镇静组不良反应发生率显著低于常规镇静组( < 0.05)。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/f4d6/9018195/fee2bf7384b1/JHE2022-3486313.001.jpg

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