Berberi Antoine N, Aoun Georges T, Aad Georges P, Khalaf Emile N
Department of Oral and Maxillofacial Surgery, Faculty of Dental Medicine, Lebanese University, Beirut, Lebanon.
Oral Medicine and Maxillofacial Radiology, Faculty of Dental Medicine, Lebanese University, Beirut, Lebanon.
J Oral Maxillofac Pathol. 2022 Feb;26(Suppl 1):S46-S50. doi: 10.4103/jomfp.jomfp_94_21. Epub 2022 Feb 28.
Benign mesenchymal odontogenic tumors are lesions derived from the mesenchymal components of the tooth-forming apparatus and are consequently found within the jawbone. Benign fibro-osseous tumors are part of this category of lesions in which normal bone is substituted, initially by fibrous tissue and within time become infiltrated by osteoid and cementoid elements. They are asymptomatic, slow-growing lesions and remain undiagnosed until swelling of the face becomes prominent and they share similar radiological characteristics. Herein, we report three cases of ossifying fibroma, cemento-osseous fibroma and periapical cemento-osseous dysplasia and analyze all the correlating factors, clinical history, radiological and histological features, intraoperative appearance, and treatment with a 3-year follow-up period. Despite the advances in the identification of these pathologies, clinicians still face difficulties in their classification and the diagnosis due to overlap in both histological and radiographic findings. An accurate final diagnosis is essential for appropriate treatment and an informative prognosis.
良性间充质牙源性肿瘤是源自牙齿形成器官间充质成分的病变，因此见于颌骨内。良性纤维-骨肿瘤是这类病变的一部分，其中正常骨最初被纤维组织替代，随着时间推移被类骨质和牙骨质成分浸润。它们是无症状、生长缓慢的病变，直到面部肿胀明显才被诊断出来，并且它们具有相似的放射学特征。在此，我们报告3例骨化性纤维瘤、牙骨质-骨纤维瘤和根尖周牙骨质-骨发育异常病例，并分析所有相关因素、临床病史、放射学和组织学特征、术中表现以及3年随访期的治疗情况。尽管在这些病变的识别方面取得了进展，但由于组织学和影像学表现存在重叠，临床医生在其分类和诊断方面仍面临困难。准确的最终诊断对于恰当的治疗和提供信息的预后至关重要。
