鱼骨骼肌丝氨酸蛋白酶对肌原纤维的作用。

Action of a serine proteinase from fish skeletal muscle on myofibrils.

作者信息

Busconi L, Folco E J, Martone C B, Trucco R E, Sanchez J J

出版信息

Arch Biochem Biophys. 1987 Jan;252(1):329-33. doi: 10.1016/0003-9861(87)90038-5.

Abstract

The action of a serine proteinase from fish skeletal muscle on myofibrils was studied. The enzyme was able to destroy the structural integrity of myofibrils, and to degrade both their major contractile and cytoskeletal constituent proteins. Proteolysis could be completely prevented by the addition of a trypsin inhibitor isolated from the same muscle.

摘要

研究了一种来自鱼骨骼肌的丝氨酸蛋白酶对肌原纤维的作用。该酶能够破坏肌原纤维的结构完整性，并降解其主要的收缩和细胞骨架组成蛋白。添加从同一肌肉中分离出的胰蛋白酶抑制剂可完全阻止蛋白水解。