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[胫骨慢性骨髓炎;使用生物活性玻璃作为一种治疗选择]

[Chronic osteomyelitis of the tibia; use of bioactive glass as a treatment alternative].

作者信息

Mora-Zúñiga A, Cárdenas-Arellano F, Cruz-Munguía J D, Hernández-Carrillo J E

出版信息

Acta Ortop Mex. 2021 Sep-Oct;35(5):461-464.

Abstract

INTRODUCTION

Chronic osteomyelitis is a disease usually of infectious origin. The main cause is post-traumatic, it affects the bone tissue and surrounding tissue, the most frequent causative agent is Staphylococcus aureus. The most affected bone is the tibia.

CASE DESCRIPTION

A 42-year-old male with a diagnosis of chronic tibia osteomyelitis, with sequelae of previous surgical interventions, multiple antibiotic treatments, and type IV B classification by Cierny-Mader.

MATERIAL AND METHODS

Two-stage surgical management was chosen. Firstly, extensive bone and soft tissue debridement, placement of cement beads medicated with amikacin in the medullary cavity and osteoclast system for irrigation with vancomycin. In the second stage, free fibular bone grafting, fixation and stabilization with screws, bioactive glass placement in areas of interface between stabilized fibula and posterior tibial cortex.

RESULTS

Before a multitratada chronic osteomyelitis it is necessary to individualize and evaluate treatment alternatives, in this case the surgical management in two time, the use of medication beads, bone graft and the use of bioactive glass, achieved a complete eradication of the infection and favorable clinical evolution with optimal functional recovery of affected limb.

摘要

引言

慢性骨髓炎通常是一种由感染引起的疾病。主要病因是创伤后感染,它会影响骨组织和周围组织,最常见的病原体是金黄色葡萄球菌。最常受累的骨头是胫骨。

病例描述

一名42岁男性,诊断为慢性胫骨骨髓炎,有既往手术干预、多次抗生素治疗的后遗症,Cierny-Mader分类为IV B型。

材料与方法

选择两阶段手术治疗。首先,进行广泛的骨和软组织清创,在髓腔内放置含阿米卡星的骨水泥珠,并使用破骨细胞系统用万古霉素冲洗。第二阶段,进行游离腓骨移植,用螺钉固定和稳定,在稳定的腓骨与胫骨后皮质之间的界面区域放置生物活性玻璃。

结果

对于多疗程治疗的慢性骨髓炎,有必要个体化评估治疗方案,在本病例中,分两阶段进行手术治疗,使用药物珠、骨移植和生物活性玻璃,实现了感染的完全根除以及良好的临床进展,患肢功能得到最佳恢复。

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