Cardiology, Ozel Medifema Hospital, Izmir, Turkey.
599103Cardiology, Hisar Intercontinental Hospital, Istanbul, Turkey.
Angiology. 2022 Oct;73(9):809-817. doi: 10.1177/00033197221089423. Epub 2022 Apr 22.
There is a lack of evidence regarding the short-term predictive value of serum albumin to creatinine ratio (sACR) in patients with ST-segment elevation myocardial infarction (STEMI). This study aims to investigate the relationship between sACR and short-term outcomes in these patients. We retrospectively enrolled 3057 patients with STEMI who underwent primary percutaneous coronary interventions (PCI) (median age was 58 years, and 74.3% were male). In-hospital mortality occurred in 114 (3.7%) patients. Contrast-induced nephropathy (CIN) was reported in 381 (12.4%) patients. During a 30-day follow-up, stent thrombosis (ST) occurred in 28 (.9%) patients and 30-day death in 147 (4.8%) patients. Multivariable logistic regression analysis reported that sACR was inversely associated with 30-day mortality (adjusted odds ratio (aOR): .51, 95% confidence interval (CI) .31-.82, < .001). The sACR was also inversely associated with in-hospital mortality (aOR: .71, 95% CI .56-.90, = .009), CIN (aOR: .60, 95% CI .52-.68, < .001), congestive heart failure (CHF) (aOR: .64, 95% CI .47-.87, = .007), and ST (aOR .61, 95% CI .41-.92, = .001) at 30 days. Our findings suggest that sACR is inversely associated with short-term clinical outcomes in patients with STEMI after PCI.
血清白蛋白与肌酐比值(sACR)对 ST 段抬高型心肌梗死(STEMI)患者短期预测价值的证据不足。本研究旨在探讨 sACR 与这些患者短期结局的关系。我们回顾性纳入了 3057 例接受直接经皮冠状动脉介入治疗(PCI)的 STEMI 患者(中位年龄为 58 岁,74.3%为男性)。住院期间有 114 例(3.7%)患者死亡。381 例(12.4%)患者发生对比剂肾病(CIN)。在 30 天随访期间,支架血栓形成(ST)发生 28 例(0.9%),30 天死亡 147 例(4.8%)。多变量逻辑回归分析显示,sACR 与 30 天死亡率呈负相关(校正比值比(aOR):0.51,95%置信区间(CI):0.31-0.82,<0.001)。sACR 与住院期间死亡率(aOR:0.71,95% CI:0.56-0.90,=0.009)、CIN(aOR:0.60,95% CI:0.52-0.68,<0.001)、充血性心力衰竭(CHF)(aOR:0.64,95% CI:0.47-0.87,=0.007)和 30 天 ST(aOR:0.61,95% CI:0.41-0.92,=0.001)也呈负相关。我们的研究结果表明,sACR 与 PCI 后 STEMI 患者的短期临床结局呈负相关。