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血管内治疗急性缺血性脑卒中的麻醉考虑因素。

Anesthetic consideations for endovascular treatment of acute ischemic stroke.

机构信息

Toronto Western Hospital, University Health Network, Toronto, ON, Canada.

Department of Anesthesiology, Pharmacology & Therapeutics, The University of British Columbia, Vancouver, BC, Canada.

出版信息

Can J Anaesth. 2022 May;69(5):658-673. doi: 10.1007/s12630-022-02224-1. Epub 2022 Apr 22.

Abstract

PURPOSE

The purpose of this Continuing Professional Development module is to provide information pertaining to anesthetic considerations and management of endovascular thrombectomy (EVT) for patients with acute ischemic stroke.

PRINCIPAL FINDINGS

Acute ischemic stroke is a devastating neurologic disorder and timely intervention is key to a good neurologic outcome. This article provides an overview of three important concepts: pathophysiology and disease characteristics of acute ischemic stroke, and the procedural and anesthetic aspects of EVT. Key considerations include recognition of stroke symptoms, timing and urgency of intervention, procedural considerations for anesthesiologists, risks and benefits of different anesthetic techniques, and a summary of recent guidelines. In particular, current recommendations for blood pressure management in this setting are reviewed.

CONCLUSIONS

Timely intervention for patients with acute ischemic stroke is of utmost importance. Endovascular thrombectomy is a minimally invasive procedure that has evolved over recent decades and improves outcomes for selected patients with ischemic stroke. Anesthesiologists should have a good understanding of potential complications and anesthetic options. Recent randomized trials have shown that both general anesthesia and sedation are associated with good outcomes; the anesthetic approach should be individualized and may vary by institution. Careful monitoring and maintenance of hemodynamic goals are critical, as is effective communication with the multidisciplinary team.

摘要

目的

本继续职业发展模块旨在提供与急性缺血性脑卒中患者血管内血栓切除术 (EVT) 相关的麻醉注意事项和管理信息。

主要发现

急性缺血性脑卒中是一种破坏性的神经系统疾病,及时干预是获得良好神经结局的关键。本文概述了三个重要概念:急性缺血性脑卒中的病理生理学和疾病特征,以及 EVT 的程序和麻醉方面。关键考虑因素包括识别脑卒中症状、干预的时间和紧迫性、麻醉医生的程序注意事项、不同麻醉技术的风险和益处,以及最近指南的摘要。特别是,本文回顾了该环境下血压管理的当前建议。

结论

急性缺血性脑卒中患者的及时干预至关重要。血管内血栓切除术是一种微创程序,近年来得到了发展,可改善选定的缺血性脑卒中患者的结局。麻醉医生应充分了解潜在的并发症和麻醉选择。最近的随机试验表明,全身麻醉和镇静均与良好结局相关;麻醉方法应个体化,并可能因机构而异。仔细监测和维持血流动力学目标至关重要,与多学科团队进行有效的沟通也是如此。

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