Hartung G H, Myhre L G, Tucker D M, Burns J W
Aviat Space Environ Med. 1987 Jan;58(1):24-8.
Eleven trained men (aged 34.5 +/- 2 yrs) were studied during a 16.1 km run in the heat (Ta = 30.2 degrees C). Fasting blood samples were taken prior to the run and at 6.4, 12.9, and 16.1 km, and 3 h recovery. Serum or plasma glucose, insulin, glucagon, glycerol, and catecholamines were measured. Mean values were: exercise intensity, 80% of VO2max; final rectal temperature, 39.9 degrees C; and weight loss, 4.0%. Glucose increased 61% by 6.4 km, then decreased significantly by 16.1 km. Glycerol increased by 415% at 6.4 km, and continued to increase throughout the run. Epinephrine increased progressively during the run, but norepinephrine increased at 6.4 km, and did not change further during the exercise. Insulin increased slightly at 6.4 km, then decreased significantly from 6.4-16.1 km. Glucagon increased from 6.4-12.9 km and remained elevated at 3 h recovery. Hormone and substrate measurements obtained only before and after prolonged exercise may not reflect changes that occur during the course of the exercise. The observed insulin-glucagon relationships vary from previous findings in nontrained subjects at lower exercise intensities.
11名受过训练的男性（年龄34.5±2岁）在炎热环境（Ta = 30.2摄氏度）下进行16.1公里跑步时接受了研究。在跑步前、6.4公里处、12.9公里处、16.1公里处以及恢复3小时后采集空腹血样。检测血清或血浆中的葡萄糖、胰岛素、胰高血糖素、甘油和儿茶酚胺。平均值如下：运动强度为最大摄氧量的80%；最终直肠温度为39.9摄氏度；体重减轻4.0%。葡萄糖在6.4公里处增加了61%，然后在16.1公里处显著下降。甘油在6.4公里处增加了415%，并在整个跑步过程中持续增加。肾上腺素在跑步过程中逐渐增加，但去甲肾上腺素在6.4公里处增加，在运动过程中不再进一步变化。胰岛素在6.4公里处略有增加，然后在6.4至16.1公里处显著下降。胰高血糖素在6.4至12.9公里处增加，并在恢复3小时时仍保持升高。仅在长时间运动前后获得的激素和底物测量结果可能无法反映运动过程中发生的变化。观察到的胰岛素 - 胰高血糖素关系与之前在较低运动强度下非训练受试者的研究结果不同。
