Traumatic Brain Injury Center of Excellence (TBI CoE), Research and Development Directorate (J-9), Defense Health Agency, Fort Carson, Colorado (Drs Vander Vegt, Hershaw, and Souvignier and Ms Hill-Pearson); Warrior Recovery Center, Evans Army Community Hospital, Fort Carson, Colorado (Drs Vander Vegt, Hershaw, Bobula, and Souvignier and Ms Hill-Pearson); General Dynamics Information Technology, Falls Church, Virginia (Drs Vander Vegt and Hershaw and Ms Hill-Pearson); and Michigan State University, East Lansing (Ms Loftin).
J Head Trauma Rehabil. 2022;37(6):380-389. doi: 10.1097/HTR.0000000000000777. Epub 2022 Apr 21.
To compare clinical outcomes between active duty service members receiving generalized versus individualized vestibular rehabilitation treatment (GVRT and IVRT, respectively) for persistent vestibular-related symptoms following mild traumatic brain injury (mTBI).
An outpatient TBI rehabilitation clinic.
Fifty-seven participants with persistent vestibular-related symptoms following mTBI were randomly assigned to the GVRT ( n = 28) or IVRT ( n = 29) group, stratified by dizziness-related impairment severity. Forty-two participants ( n = 21 per group) completed the posttreatment evaluation and were included in analyses.
We employed a single-site, randomized, pre-/posttest experimental design. The GVRT program consisted of eight 45-minute group-based treatment sessions and IVRT consisted of three 30-minute one-on-one treatment sessions both to be completed within 8 weeks. Group assignment was not blinded to study personnel or participants. Research evaluations were completed approximately 2 weeks prior to treatment initiation and following treatment completion.
Outcome measures included Dizziness Handicap Inventory (DHI) and Activities-specific Balance Confidence Scale (ABC) total scores, Sensory Organization Test (SOT) composite equilibrium and sensory input ratio scores, Head Shake SOT (HS-SOT) conditions 2 and 5, and horizontal and vertical Dynamic Visual Acuity. Separate mixed-effects models were used to compare clinical outcomes between the GVRT and IVRT groups.
Both groups demonstrated significant improvement from pre- to posttreatment on self-reported dizziness-related impairment (DHI [ F(1,41) = 16.28, P < .001]) and balance performance with and without head movement (composite equilibrium score [ F(1,41) = 16.58, P < .001, effect size [ES] = 0.43], somatosensory [ F(1,41) = 6.79, P = .013, ES = 0.26], visual [ F(1,41) = 6.49, P = .015, ES = 0.29], vestibular [ F(1,41) = 22.31, P < .001, ES = 0.55], and HS-SOT condition 5 [ F(1,38) = 23.98, P < .001, ES = 0.64]). Treatment effects did not differ between groups on any of the outcome measures.
We provide preliminary evidence that differences in clinical outcomes do not exist between participants receiving generalized versus individualized VR. Further research is needed to determine comparative effectiveness between these 2 treatment approaches for persistent vestibular-related symptoms following mTBI.
比较患有持续性前庭相关症状的现役军人在接受常规化与个体化前庭康复治疗(GVRT 和 IVRT)后的临床结局,这些患者均患有轻度创伤性脑损伤(mTBI)。
门诊创伤性脑损伤康复诊所。
57 名患有持续性前庭相关症状的 mTBI 患者被随机分配到 GVRT(n=28)或 IVRT(n=29)组,按与头晕相关的损害严重程度进行分层。42 名参与者(每组 n=21)完成了治疗后评估,并纳入分析。
我们采用了单站点、随机、前后测试实验设计。GVRT 方案包括 8 次 45 分钟的集体治疗,IVRT 包括 3 次 30 分钟的一对一治疗,均需在 8 周内完成。组分配对研究人员或参与者均不设盲。研究评估在治疗开始前大约 2 周和治疗完成后进行。
结局测量包括头晕残疾量表(DHI)和活动特异性平衡信心量表(ABC)总分、感觉组织测试(SOT)复合平衡和感觉输入比评分、头摇动 SOT(HS-SOT)条件 2 和 5 以及水平和垂直动态视力。分别使用混合效应模型比较 GVRT 和 IVRT 组之间的临床结局。
两组患者在报告的头晕相关损害(DHI[F(1,41)=16.28,P<.001])和有或无头动的平衡表现(复合平衡评分[F(1,41)=16.58,P<.001,效应量[ES]=0.43]、躯体感觉[F(1,41)=6.79,P=.013,ES=0.26]、视觉[F(1,41)=6.49,P=.015,ES=0.29]、前庭[F(1,41)=22.31,P<.001,ES=0.55]和 HS-SOT 条件 5[F(1,38)=23.98,P<.001,ES=0.64])方面均有显著改善。在任何结局测量上,治疗效果均无组间差异。
我们提供了初步证据,表明接受常规化与个体化 VR 的患者在临床结局上没有差异。需要进一步研究以确定这两种治疗方法对 mTBI 后持续性前庭相关症状的比较效果。