Soldati Gino, Demi Marcello
Ippocrate Medical Center, 55032 Lucca, Italy.
Department of Bioengineering, Fondazione Toscana Gabriele Monasterio, 56126 Pisa, Italy.
Diagnostics (Basel). 2022 Mar 29;12(4):838. doi: 10.3390/diagnostics12040838.
In lung ultrasound (LUS), the interactions between the acoustic pulse and the lung surface (including the pleura and a small subpleural layer of tissue) are crucial. Variations of the peripheral lung density and the subpleural alveolar shape and its configuration are typically connected to the presence of ultrasound artifacts and consolidations. COVID-19 pneumonia can give rise to a variety of pathological pulmonary changes ranging from mild diffuse alveolar damage (DAD) to severe acute respiratory distress syndrome (ARDS), characterized by peripheral bilateral patchy lung involvement. These findings are well described in CT imaging and in anatomopathological cases. Ultrasound artifacts and consolidations are therefore expected signs in COVID-19 pneumonia because edema, DAD, lung hemorrhage, interstitial thickening, hyaline membranes, and infiltrative lung diseases when they arise in a subpleural position, generate ultrasound findings. This review analyzes the structure of the ultrasound images in the normal and pathological lung given our current knowledge, and the role of LUS in the diagnosis and monitoring of patients with COVID-19 lung involvement.
在肺部超声(LUS)中,声脉冲与肺表面(包括胸膜和胸膜下一小层组织)之间的相互作用至关重要。肺外周密度以及胸膜下肺泡形状及其结构的变化通常与超声伪像和实变的存在有关。新型冠状病毒肺炎(COVID-19)可导致多种病理性肺部改变,从轻度弥漫性肺泡损伤(DAD)到严重急性呼吸窘迫综合征(ARDS),其特征为双侧外周肺部片状受累。这些发现在CT成像和解剖病理学病例中已有充分描述。因此,超声伪像和实变是COVID-19肺炎的预期征象,因为水肿、DAD、肺出血、间质增厚、透明膜以及浸润性肺疾病出现在胸膜下位置时会产生超声表现。本综述根据我们目前的知识分析了正常和病理性肺的超声图像结构,以及LUS在COVID-19肺部受累患者诊断和监测中的作用。