Pantea-Roșan Larisa Renata, Bungau Simona Gabriela, Radu Andrei-Flavius, Pantea Vlad Alin, Moisi Mădălina Ioana, Vesa Cosmin Mihai, Behl Tapan, Nechifor Aurelia Cristina, Babes Elena Emilia, Stoicescu Manuela, Gitea Daniela, Iovanovici Diana Carina, Bustea Cristiana
Department of Medical Disciplines, Faculty of Medicine and Pharmacy, University of Oradea, 410073 Oradea, Romania.
Doctoral School of Biological and Biomedical Sciences, University of Oradea, 410087 Oradea, Romania.
Diagnostics (Basel). 2022 Apr 8;12(4):932. doi: 10.3390/diagnostics12040932.
The incidence of the no-reflow (NR) phenomenon varies depending on the diagnostic criteria used. If just the angiographic criteria are considered (i.e., a degree of thrombolysis in myocardial infarction ≤2), it will be found that the incidence of NR is quite low; on the other hand, when the myocardial NR is taken into account (i.e., a decrease in the quality of myocardial reperfusion expressed by the degree of myocardial blush), the real incidence is higher. Thus, the early establishment of a diagnosis of NR and the administration of specific treatment can lead to its reversibility. Otherwise, regardless of the follow-up period, patients with NR have a poor prognosis. In the present work, we offer a comprehensive perspective on diagnostic tools for NR detection, for improving the global management of patients with arterial microvasculature damage, which is a topic of major interest in the cardiology field, due to its complexity and its link with severe clinical outcomes.
无复流（NR）现象的发生率因所采用的诊断标准而异。如果仅考虑血管造影标准（即心肌梗死溶栓分级≤2级），会发现NR的发生率相当低；另一方面，当考虑心肌无复流时（即通过心肌 blush 分级表示的心肌再灌注质量下降），实际发生率更高。因此，早期诊断NR并给予特异性治疗可使其逆转。否则，无论随访期如何，NR患者的预后都很差。在本研究中，我们提供了关于NR检测诊断工具的全面观点，以改善对动脉微血管损伤患者的整体管理，由于其复杂性及其与严重临床结局的关联，这是心脏病学领域一个备受关注的主题。
