Sefidkar Narmin, Fathizadeh Samira, Nemati Fatemeh, Simserides Constantinos
Department of Physics, Urmia University of Technology, Urmia 5716693187, Iran.
Department of Physics, National and Kapodistrian University of Athens, Panepistimiopolis, Zografos, GR-15784 Athens, Greece.
Materials (Basel). 2022 Apr 10;15(8):2779. doi: 10.3390/ma15082779.
Energy transport within biological systems is critical for biological functions in living cells and for technological applications in molecular motors. Biological systems have very complex dynamics supporting a large number of biochemical and biophysical processes. In the current work, we study the energy transport along protein chains. We examine the influence of different factors such as temperature, salt concentration, and external mechanical drive on the energy flux through protein chains. We obtain that energy fluctuations around the average value for short chains are greater than for longer chains. In addition, the external mechanical load is the most effective agent on bioenergy transport along the studied protein systems. Our results can help design a functional nano-scaled molecular motor based on energy transport along protein chains.
生物系统中的能量传输对于活细胞中的生物功能以及分子马达的技术应用至关重要。生物系统具有非常复杂的动力学，支持大量的生化和生物物理过程。在当前的工作中，我们研究了沿蛋白质链的能量传输。我们研究了不同因素，如温度、盐浓度和外部机械驱动对通过蛋白质链的能量通量的影响。我们发现，短链的能量围绕平均值的波动大于长链。此外，在所研究的蛋白质系统中，外部机械负载是对生物能量传输最有效的因素。我们的结果有助于基于沿蛋白质链的能量传输设计功能性纳米级分子马达。
