Sławińska Martyna, Kamińska-Winciorek Grażyna, Balicka Urszula, Żawrocki Anton, Nowicki Roman J, Sobjanek Michał, Errichetti Enzo
Department of Dermatology, Venereology and Allergology, Faculty of Medicine, Medical University of Gdańsk, 80-214 Gdańsk, Poland.
Department of Bone Marrow Transplantation and Oncohematology, Skin Cancer and Melanoma Team, Maria Sklodowska-Curie National Research Institute of Oncology, Gliwice Branch, 44-102 Gliwice, Poland.
Cancers (Basel). 2022 Apr 10;14(8):1920. doi: 10.3390/cancers14081920.
Little is known about the correlation between lesion- and patient-related variables and the dermoscopic features of blue nevi. The aim of the study was dermoscopic analysis of blue nevi in association with patient- and lesion-related variables, with a special interest in structures whose prevalence has not been previously reported. This was a double-center, retrospective study, which included the analysis of histopathologically confirmed blue nevi ( = 93). There was no difference in the frequency of the observed dermoscopic features according to patients' gender and age. Pink structureless areas were more common in patients with I/II Fitzpatrick skin phototypes as well as in the patients with photodamaged skin, while blue prominent skin markings over brownish/blue-gray background occurred exclusively in patients with phototype III. Structures of previously unreported prevalence in blue nevi were skin-colored circles (present in 32.3%), gray circles (2.2%), follicular ostia with no pigmentation (18.4%; present exclusively on the face), blue skin markings over brownish background (present in 18.2%; detected only on the limbs) and dark brown polygons (one lesion located on the lower extremity). Dermoscopic presentation of blue nevi may vary according to the patient's phototype and lesion size/localization rather than gender and age.
关于病损相关和患者相关变量与蓝痣皮肤镜特征之间的相关性，目前所知甚少。本研究的目的是结合患者和病损相关变量对蓝痣进行皮肤镜分析，特别关注那些此前未报道过其发生率的结构。这是一项双中心回顾性研究，包括对93例经组织病理学确诊的蓝痣进行分析。根据患者的性别和年龄，所观察到的皮肤镜特征的频率没有差异。粉色无结构区域在I/II型菲茨帕特里克皮肤光类型患者以及皮肤光损伤患者中更为常见，而棕色/蓝灰色背景上的蓝色明显皮肤斑纹仅出现在III型光类型患者中。蓝痣中此前未报道过发生率的结构有肤色圆圈（占32.3%）、灰色圆圈（2.2%）、无色素沉着的毛囊口（18.4%；仅出现在面部）、棕色背景上的蓝色皮肤斑纹（占18.2%；仅在四肢检测到）和深棕色多边形（1个病损位于下肢）。蓝痣的皮肤镜表现可能因患者的光类型和病损大小/部位而异，而非性别和年龄。
