López-Guerrero José Antonio, Mendiola Marta, Pérez-Fidalgo José Alejandro, Romero Ignacio, Torres Ana, Recalde Delia, Molina Elena, Gómez-Raposo César, Levin Ana M, Herrero Ana, Alarcón Jesús, Esteban Carmen, Marquina Gloria, Rubio María Jesús, Guerra Eva, Sánchez-Lorenzo Luisa, Gálvez-Montosa Fernando, de Juan Ana, Churruca Cristina, Gallego Alejandro, González-Martín Antonio
Laboratorio de Biología Molecular y Biobanco, Fundación Instituto Valenciano de Oncología, 46009 Valencia, Spain.
Unidad Mixta de Investigación en Cáncer IVO-CIPF, Centro de Investigación Príncipe Felipe (CIPF), 46012 Valencia, Spain.
Cancers (Basel). 2022 Apr 13;14(8):1965. doi: 10.3390/cancers14081965.
Patient registries linked to biorepositories constitute a valuable asset for clinical and translational research in oncology. The Spanish Group of Ovarian Cancer Research (GEICO), in collaboration with the Spanish Biobank Network (RNBB), has developed a multicentre, multistakeholder, prospective virtual clinical registry (VCR) associated with biobanks for the collection of real-world data and biological samples of gynaecological cancer patients. This collaborative project aims to promote research by providing broad access to high-quality clinical data and biospecimens for future research according to the needs of investigators and to increase diagnostic and therapeutic opportunities for gynaecological cancer patients in Spain. The VCR will include the participation of more than 60 Spanish hospitals entering relevant clinical information in harmonised electronic case report forms (eCRFs) in four different cohorts: ovarian, endometrial, cervical, and rare gynaecological cancers (gestational trophoblastic disease). Initial data for the cases included till December 2021 are presented. The model described herein establishes a real-world win-win collaboration between multicentre structures, promoted and supported by GEICO, that will contribute to the success of translational research in gynaecological cancer.
与生物样本库相关联的患者登记系统是肿瘤学临床和转化研究的宝贵资产。西班牙卵巢癌研究小组（GEICO）与西班牙生物样本库网络（RNBB）合作，开发了一个多中心、多利益相关方的前瞻性虚拟临床登记系统（VCR），该系统与生物样本库相关联，用于收集妇科癌症患者的真实世界数据和生物样本。这个合作项目旨在通过根据研究人员的需求为未来研究广泛提供高质量临床数据和生物样本，来促进研究，并增加西班牙妇科癌症患者的诊断和治疗机会。VCR将包括60多家西班牙医院的参与，这些医院将在四种不同队列（卵巢癌、子宫内膜癌、宫颈癌和罕见妇科癌症（妊娠滋养细胞疾病））中，以统一的电子病例报告表（eCRF）输入相关临床信息。本文展示了截至2021年12月所纳入病例的初始数据。本文所述模型在GEICO推动和支持下，在多中心结构之间建立了一种真实世界的双赢合作关系，这将有助于妇科癌症转化研究的成功。
