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对新冠疫苗安全性的担忧是苏丹糖尿病患者疫苗接种率低的原因。

The Concern of COVID-19 Vaccine Safety Is behind Its Low Uptake among Patients with Diabetes Mellitus in Sudan.

作者信息

Omar Saeed M, Khalil Rehana, Adam Ishag, Al-Wutayd Osama

机构信息

Department of Medicine, Faculty of Medicine, Gadarif University, Gadarif 32211, Sudan.

Department of Family and Community Medicine, Unaizah College of Medicine and Medical Sciences, Qassim University, Unaizah 56219, Saudi Arabia.

出版信息

Vaccines (Basel). 2022 Mar 29;10(4):527. doi: 10.3390/vaccines10040527.

DOI:10.3390/vaccines10040527
PMID:35455276
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9031942/
Abstract

Diabetic patients are vulnerable to developing severe complications and have a higher risk of death due to COVID-19 infection. Vaccination remains the mainstay during the current situation to mitigate the risks related to COVID-19 infection. Therefore, the aim of the current study was to assess the vaccination status and the factors associated with COVID-19 vaccine uptake among patients with diabetes mellitus (DM) in Sudan. A hospital-based cross-sectional study was conducted from January to February 2022 at Gadarif Hospital in eastern Sudan. Information on sociodemographics, the contracting of COVID-19 during the pandemic, beliefs toward COVID-19 vaccinations, and barriers related to COVID-19 vaccinations was obtained through an interview questionnaire among adult (≥18 years) patients with DM. Bivariate and multinomial logistic regression analyses performed. A total of 568 diabetic patients were enrolled, with a mean (SD) age of 53.07 (12.69) years. The majority of the participants were female (67.6%), urban residents (63.4%), uneducated (60.6%) and employed (73.2%). There was a history of COVID-19 in 97.4% of participants, and 29.2% of them had hypertension along with DM. About 31% received the vaccine, out of which 17.9% received the first dose, 13.2% received the second dose, and 0.2% received the third dose. Multinomial logistic regression analysis showed a significant association between belief in the safety of the COVID-19 vaccine and having had two doses of it (adjusted Odds ratio = 20.42, p < 0.001). The prevalence of COVID-19 infection was high, while the rate of COVID-19 vaccination uptake was low and inadequate among the participants. Appropriate health education and targeted interventions toward awareness of safety concerns are highly recommended.

摘要

糖尿病患者易发生严重并发症,且因感染新冠病毒而死亡的风险更高。在当前形势下,接种疫苗仍是降低与新冠病毒感染相关风险的主要手段。因此,本研究的目的是评估苏丹糖尿病患者的疫苗接种状况以及与新冠疫苗接种率相关的因素。2022年1月至2月在苏丹东部加达里夫医院开展了一项基于医院的横断面研究。通过对成年(≥18岁)糖尿病患者进行访谈问卷,获取了社会人口统计学信息、疫情期间感染新冠病毒的情况、对新冠疫苗接种的看法以及与新冠疫苗接种相关的障碍。进行了双变量和多项逻辑回归分析。共纳入568例糖尿病患者,平均(标准差)年龄为53.07(12.69)岁。大多数参与者为女性(67.6%)、城市居民(63.4%)、未受过教育(60.6%)且有工作(73.2%)。97.4%的参与者有新冠病毒感染史,其中29.2%同时患有高血压和糖尿病。约31%的人接种了疫苗,其中17.9%接种了第一剂,13.2%接种了第二剂,0.2%接种了第三剂。多项逻辑回归分析显示,对新冠疫苗安全性的信念与接种两剂疫苗之间存在显著关联(调整后的优势比 = 20.42,p < 0.001)。参与者中新冠病毒感染的患病率较高,而新冠疫苗接种率较低且不足。强烈建议进行适当的健康教育和针对安全问题认知的有针对性干预。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ed3/9031942/36ac340c720e/vaccines-10-00527-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ed3/9031942/36ac340c720e/vaccines-10-00527-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/2ed3/9031942/36ac340c720e/vaccines-10-00527-g001.jpg

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