Ejezie Chinenye Lynette, Osaghae Ikponmwosa, Ayieko Sylvia, Cuccaro Paula
Department of Health Promotion and Behavioral Sciences, The University of Texas School of Public Health, 1200 Pressler St, Houston, TX 77030, USA.
Department of Investigational Cancer Therapeutics, The University of MD Anderson Cancer Center, Houston, TX 77030, USA.
Vaccines (Basel). 2022 Apr 8;10(4):577. doi: 10.3390/vaccines10040577.
The 9-valent human papillomavirus (9-vHPV) vaccine uptake rate among adolescents has improved over the years; however, little is known about the adherence to the recommended dosing schedule. This study examines the prevalence and factors associated with adherence to the recommended 9vHPV vaccination dosing schedule among adolescents aged 13 to 17 years. The cross-sectional study was conducted using the 2019-2020 National Immunization Survey-Teen. The parents of 34,619 adolescents were included in our analyses. The overall up-to-date (UTD) prevalence was 57.1%. The UTD prevalence was 60.0% among females and 54.2% among males. Adolescents aged 16 years had the highest UTD prevalence of 63.0%. The UTD prevalence was 61.6% among Hispanics and 54.7% among non-Hispanic Whites. Overall, compared to females, males had 14% lower odds of UTD. The odds of UTD were 1.91 times, 2.08 times, and 1.98 times higher among adolescents aged 15-17 years, respectively, compared to those aged 13 years. Moreover, region, poverty, insurance status, mothers' educational level, and provider recommendation were associated with UTD. Our findings show that adherence to the recommended 9vHPV vaccine schedule is low in the US. Targeted public health efforts are needed to improve the rates of adherence to the recommended 9vHPV dose schedule.
多年来，青少年中九价人乳头瘤病毒（9-vHPV）疫苗的接种率有所提高；然而，对于是否遵循推荐的接种程序却知之甚少。本研究调查了13至17岁青少年中遵循推荐的9vHPV疫苗接种程序的流行情况及相关因素。这项横断面研究使用了2019 - 2020年全国青少年免疫调查。我们的分析纳入了34,619名青少年的父母。总体最新接种率为57.1%。女性的最新接种率为60.0%，男性为54.2%。16岁青少年的最新接种率最高，为63.0%。西班牙裔的最新接种率为61.6%，非西班牙裔白人则为54.7%。总体而言，与女性相比，男性的最新接种几率低14%。与13岁的青少年相比，15 - 17岁的青少年最新接种几率分别高出1.91倍、2.08倍和1.98倍。此外，地区、贫困状况、保险状况、母亲的教育水平以及医疗服务提供者的建议都与最新接种情况有关。我们的研究结果表明，美国遵循推荐的9vHPV疫苗接种程序的情况较差。需要有针对性地开展公共卫生工作，以提高遵循推荐的9vHPV疫苗接种程序的比例。
