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在胸腰椎脊柱手术中使用术中三维导航是否是术后感染的危险因素?

Is the Use of Intraoperative 3D Navigation for Thoracolumbar Spine Surgery a Risk Factor for Post-Operative Infection?

作者信息

Berman Daniel, Eleswarapu Ananth, Krystal Jonathan, Hoang Henry

机构信息

Montefiore Medical Center, Bronx, NY 10467, USA.

Albert Einstein College of Medicine, Bronx, NY 10461, USA.

出版信息

J Clin Med. 2022 Apr 10;11(8):2108. doi: 10.3390/jcm11082108.

DOI:10.3390/jcm11082108
PMID:35456201
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9025334/
Abstract

Pedicle screw fixation is a technique used to provide rigid fixation in thoracolumbar spine surgery. Safe intraosseous placement of pedicle screws is necessary to provide optimal fixation as well as to avoid damage to adjacent anatomic structures. Despite the wide variety of techniques available, none thus far has been able to fully eliminate the risk of malpositioned screws. Intraoperative 3-dimensional navigation (I3DN) was developed to improve accuracy in the placement of pedicle screws. To our knowledge, no previous studies have investigated whether infection rates are higher with I3DN. A single-institution, retrospective study of patients age > 18 undergoing thoracolumbar fusion and instrumentation was carried out and use of I3DN was recorded. The I3DN group had a significantly greater rate of return to the operating room for culture-positive incision and drainage (17 (4.1%) vs. 1 (0.6%), p = 0.025). In multivariate analysis, the use of I3DM did not reach significance with an OR of 6.49 (0.84−50.02, p = 0.073). Post-operative infections are multifactorial and potential infection risks associated with I3DN need to be weighed against the safety benefits of improved accuracy of pedicle screw positioning.

摘要

椎弓根螺钉固定是一种用于胸腰椎手术中提供坚强固定的技术。椎弓根螺钉在骨内的安全置入对于实现最佳固定以及避免损伤相邻解剖结构而言是必要的。尽管有各种各样的可用技术,但迄今为止尚无一种能够完全消除螺钉位置不当的风险。术中三维导航(I3DN)的开发旨在提高椎弓根螺钉置入的准确性。据我们所知,此前尚无研究调查过I3DN是否会使感染率更高。我们进行了一项针对年龄大于18岁接受胸腰椎融合及内固定术患者的单机构回顾性研究,并记录了I3DN的使用情况。I3DN组因切口培养阳性而返回手术室进行切开引流的比例显著更高(17例(4.1%)对1例(0.6%),p = 0.025)。在多因素分析中,I3DM的使用未达到显著水平,比值比为6.49(0.84 - 50.02,p = 0.073)。术后感染是多因素导致的,与I3DN相关的潜在感染风险需要与椎弓根螺钉定位准确性提高带来的安全益处相权衡。

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本文引用的文献

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Accuracy of Freehand versus Navigated Thoracolumbar Pedicle Screw Placement in Patients with Metastatic Tumors of the Spine.徒手与导航下胸腰椎椎弓根螺钉置入在脊柱转移性肿瘤患者中的准确性
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Accuracy of pedicle screw placement by fluoroscopy, a three-dimensional printed model, local electrical conductivity measurement device, and intraoperative computed tomography navigation in scoliosis patients.荧光透视、三维打印模型、局部电导率测量装置及术中计算机断层扫描导航在脊柱侧弯患者中椎弓根螺钉置入的准确性
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What are the risk factors for surgical site infection after spinal fusion? A meta-analysis.脊柱融合术后手术部位感染的危险因素是什么?一项荟萃分析。
Eur Spine J. 2018 Oct;27(10):2469-2480. doi: 10.1007/s00586-018-5733-7. Epub 2018 Aug 20.
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Incidence and risk factors of wound complications in long segment instrumented thoracolumbar spinal fusions: a retrospective study.长节段器械辅助胸腰椎脊柱融合术中伤口并发症的发生率及危险因素:一项回顾性研究
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