Payer Juraj, Smaha Juraj, Kužma Martin, Killinger Zdenko, Jackuliak Peter
Vnitr Lek. 2021 Winter;67(5):284-290.
In contrast to postmenopausal women diagnostic process and treatment of premenopausal osteoporosis in young women reamin poorly defined. A low bone mineral density in premenopausal women is not associated with the same risk of fractures as in postmenopausal women, therefore diagnosis requires not only densitometric examination but depends on the consideration of other risk factors. Most cases of premenopausal osteoporosis are associated with chronic diseases affecting bone metabolism. Treatment of the underlying disease may improve bone density as well as bone quality. Rarely, a bone-specific antiporotic therapy may be used, although quality evidence is scarce. This article will review current opinion on definition, diagnosis and treatment of premenopausal osteoporosis.
与绝经后女性相比，年轻女性绝经前骨质疏松症的诊断过程和治疗仍不明确。绝经前女性的低骨密度与绝经后女性的骨折风险不同，因此诊断不仅需要骨密度检查，还取决于对其他风险因素的考虑。大多数绝经前骨质疏松症病例与影响骨代谢的慢性疾病有关。治疗基础疾病可能会改善骨密度和骨质量。尽管高质量证据稀缺，但很少会使用针对骨骼的抗骨质疏松治疗。本文将综述目前关于绝经前骨质疏松症的定义、诊断和治疗的观点。
