Medicine, University of Malaya, Kuala Lumpur, Malaysia
Medicine, University of Malaya, Kuala Lumpur, Malaysia.
BMJ Support Palliat Care. 2024 Jan 8;13(e3):e1117-e1125. doi: 10.1136/bmjspcare-2021-003349.
Suffering is common among patients with advanced cancer. The practice of mindfulness during patient care can potentially reduce suffering. We aimed to examine the efficacy of mindfulness-based supportive therapy (MBST) on reducing suffering in patients with advanced cancer.
We conducted a parallel-group, single-blinded, randomised controlled trial at the University of Malaya Medical Centre, Malaysia. Seventy-three patients with advanced cancer with an overall suffering score ≥4/10 based on the Suffering Pictogram were recruited and randomly assigned into either the MBST group (n=34) or the control group (n=39).
There was a statistically significant reduction in the overall suffering score in the MBST group compared with the control group (U=432.5, median=-2.0, median=-1.0, z=-2.645, p=0.008). There was also significant improvement in the total Hospital Anxiety and Depression Scale score (U=483.5, median=-4.0, median=-3.0, z=-1.994, p=0.046), and the total Functional Assessment of Chronic Illness Therapy-Spiritual Well-Being score (U=252.0, median=+14.5, median=+5.0, z=-4.549, p=0.000) in the MBST group compared with the control group.
The results provided evidence that the practice of MBST during patient care could promote positive psychosocial outcomes.
晚期癌症患者常伴有痛苦。在患者护理中实施正念实践可能会减轻痛苦。我们旨在检验正念支持性治疗（MBST）对减轻晚期癌症患者痛苦的疗效。
我们在马来西亚马来亚大学医学中心进行了一项平行组、单盲、随机对照试验。共招募了 73 名总体痛苦评分≥10 分的晚期癌症患者（根据痛苦图像评分为 4/10），并随机分为 MBST 组（n=34）或对照组（n=39）。
与对照组相比，MBST 组的总体痛苦评分有统计学显著降低（U=432.5，中位数=-2.0，中位数=-1.0，z=-2.645，p=0.008）。MBST 组的医院焦虑和抑郁量表总分（U=483.5，中位数=-4.0，中位数=-3.0，z=-1.994，p=0.046）和慢性疾病治疗-精神健康功能评估总分（U=252.0，中位数=+14.5，中位数=+5.0，z=-4.549，p=0.000）也有显著改善。
结果提供了证据表明，在患者护理中实施 MBST 可以促进积极的心理社会结果。
