Zhonghua Wei Chang Wai Ke Za Zhi. 2022 Apr 25;25(4):277-283. doi: 10.3760/cma.j.cn441530-20220322-00111.
Currently, surgery-based comprehensive therapy plays an important role in the treatment of local advanced gastric cancer (LAGC), and standard lymph node dissection is a mainstay of gastric surgery. Radical gastrectomy with D2 lymph node dissection is widely accepted based on the international publications of randomized clinical trials, but the extent of lymph node dissection is controversial. An adequate lymph node dissection may improve prognosis and reduce complications, and D2+ lymphadenectomy may improve surgical outcomes in some selected patients. To improve the efficacy of LAGC therapies, the Gastric Cancer Association, China Anti Cancer Association took the lead and organized experts to discuss and vote, and finally formulated this expert consensus. It is hoped that this consensus can provide reference for clinicians and further improve the diagnosis and treatment level of LAGC in China.
目前，以外科手术为主的综合治疗在局部进展期胃癌（LAGC）的治疗中发挥着重要作用，标准淋巴结清扫是胃癌手术的主要手段。基于随机临床试验的国际出版物，D2淋巴结清扫的根治性胃切除术被广泛接受，但淋巴结清扫范围仍存在争议。充分的淋巴结清扫可能改善预后并减少并发症，对于某些特定患者，D2以上淋巴结切除术可能改善手术效果。为提高LAGC治疗的疗效，中国抗癌协会胃癌专业委员会牵头组织专家进行讨论和投票，最终制定了本专家共识。希望本共识能为临床医生提供参考，进一步提高我国LAGC的诊疗水平。
