Ali M A
Indian J Physiol Pharmacol. 1986 Jan-Mar;30(1):11-21.
Mesencephalic reticular formation lesions were produced bilaterally by using two epoxy-coated stainless steel electrodes. Electrolytic lesions resulted in atrophy of testes, and decreased spermatogenesis. Seminiferous tubules of lesioned rats were characterised by a general decrease in the number of cells from different generation of germinal epithelium, empty spaces, degeneration of spermatogonia, degeneration of spermatocytes I and of young spermatids. There were significant reductions in weights of the testes (P less than 0.01). Similarly the areas of cross-sections of seminiferous tubules were significantly reduced (P less than 0.05). Another note-worthy feature was a gross reduction in the complete cross section count of interstitial cells. The study strongly suggests that the mesencephalic reticular formation influences the testes and spermatogenesis.
使用两根环氧涂层不锈钢电极双侧制造中脑网状结构损伤。电解损伤导致睾丸萎缩和精子发生减少。损伤大鼠的生精小管表现为不同代生精上皮细胞数量普遍减少、出现空隙、精原细胞退化、初级精母细胞和年轻精子细胞退化。睾丸重量显著降低（P<0.01）。同样，生精小管的横截面积也显著减小（P<0.05）。另一个值得注意的特征是间质细胞的完整横切面计数大幅减少。该研究强烈表明中脑网状结构影响睾丸和精子发生。
