物质使用/滥用的新兴因素
Emerging Agents of Substance Use/Misuse.
作者信息
Michienzi Avery E, Borek Heather A
机构信息
Department of Emergency Medicine, Division of Medical Toxicology, Medical Toxicology, University of Virginia School of Medicine, University of Virginia, PO Box 800774, Charlottesville, VA 22908, USA.
Department of Emergency Medicine, Division of Medical Toxicology, Medical Toxicology, University of Virginia School of Medicine, University of Virginia, PO Box 800774, Charlottesville, VA 22908, USA.
出版信息
Emerg Med Clin North Am. 2022 May;40(2):265-281. doi: 10.1016/j.emc.2022.01.001. Epub 2022 Apr 5.
Over the last decade, the use of novel psychoactive substances (NPS) has increased. Some substances are derived from plants but an increasing number are synthetically produced. Examples include synthetic cannabinoids, synthetic cathinones, kratom, phenibut, designer opioids, and benzodiazepines. These substances have a wide variety of effects due to the varied potency with which they bind their targeted receptors. Routine immunoassay urine drug screens do not detect these substances and it is, therefore, important for clinicians to be aware of these substances to make accurate clinical diagnoses.
在过去十年中，新型精神活性物质（NPS）的使用有所增加。一些物质源自植物，但越来越多的是合成生产的。例子包括合成大麻素、合成卡西酮、 kratom、苯乙胺、设计型阿片类药物和苯二氮䓬类药物。由于这些物质与它们的靶向受体结合的效力各不相同，所以具有各种各样的效果。常规免疫分析尿液药物筛查无法检测出这些物质，因此，临床医生了解这些物质对于做出准确的临床诊断很重要。
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