Zheng Zhoulan, Guo Qianyu, Ma Dan, Wang Xuexue, Zhang Chengqiang, Wang Haiyao, Zhang Liyun, Zhang Gailian
Third Hospital of Shanxi Medical University, Shanxi Bethune Hospital, Shanxi Academy of Medical Sciences, Tongji Shanxi Hospital, Taiyuan, China.
The Fifth Clinical Medical College of Shanxi Medical University, Taiyuan, China.
Front Cardiovasc Med. 2022 Apr 6;9:835439. doi: 10.3389/fcvm.2022.835439. eCollection 2022.
Psoriatic arthritis (PsA) is a chronic autoimmune inflammatory joint disease related to psoriasis (PsO). The risk of PsA patients with cardiovascular disease (CVD) is significantly higher than that of the general population. At present, the relevant mechanism is not clear, chronic inflammation and traditional cardiovascular risk factors are the most important factors for the increased risk of CVD in PsA patients. Early assessment of the risk of PsA patients with CVD, and active control of the disease activity of PsA patients and intervention of traditional cardiovascular risk factors can delay the progression of CVD risk. This article reviews the epidemiology and pathogenesis between PsA and CVD, and reviews the latest developments in the risk assessment and management of CVD in PsA patients.
银屑病关节炎（PsA）是一种与银屑病（PsO）相关的慢性自身免疫性炎症性关节疾病。PsA患者患心血管疾病（CVD）的风险显著高于普通人群。目前，相关机制尚不清楚，慢性炎症和传统心血管危险因素是PsA患者CVD风险增加的最重要因素。早期评估PsA患者的CVD风险，积极控制PsA患者的疾病活动并干预传统心血管危险因素可延缓CVD风险的进展。本文综述了PsA与CVD之间的流行病学和发病机制，并回顾了PsA患者CVD风险评估和管理的最新进展。
