Kapeleris Audrey Pamela, Venkatachalapathy Suresh
Queen's Medical Centre, Nottingham University Hospitals NHS Trust, Nottingham, UK.
Nottingham Digestive Diseases Centre (NDDC) and NIHR Nottingham Biomedical Research Centre (BRC), Nottingham University and Nottingham University Hospitals NHS Trust, Queen's Medical Centre, Nottingham, UK.
Oxf Med Case Reports. 2022 Apr 19;2022(4):omac029. doi: 10.1093/omcr/omac029. eCollection 2022 Apr.
Severe portal hypertension in cirrhosis is a relative contraindication to major surgical intervention. Pre-surgical placement of a transjugular intrahepatic portosystemic shunt (TIPSS) can potentially reduce portal hypertension and the risk of intraoperative bleeding. Two patients in our service, with cirrhosis and portal hypertension, required abdominal surgery and underwent TIPSS placement as a potential bridging therapy. Patient 1, a 56-year-old female, successfully underwent surgery with no intraoperative complications. Patient 2, a 36-year-old male, experienced liver decompensation post-TIPSS and is currently awaiting a liver and bowel transplant. Prophylactic TIPSS placement may allow some patients with decompensated cirrhosis to successfully undergo major extrahepatic abdominal surgery. However, careful patient selection and preoperative counselling for decompensation is necessary.
肝硬化患者的严重门静脉高压是大型手术干预的相对禁忌证。术前放置经颈静脉肝内门体分流术(TIPSS)可能会降低门静脉高压和术中出血风险。我们科室的两名患有肝硬化和门静脉高压的患者需要进行腹部手术,并接受了TIPSS放置作为潜在的桥接治疗。患者1是一名56岁女性,手术成功,术中无并发症。患者2是一名36岁男性,TIPSS术后出现肝脏失代偿,目前正在等待肝肠移植。预防性TIPSS放置可能使一些失代偿性肝硬化患者成功接受大型肝外腹部手术。然而,需要仔细选择患者并对失代偿进行术前咨询。