Kawano M, Fuke Y, Nakayama T
Nihon Sanka Fujinka Gakkai Zasshi. 1987 Jan;39(1):56-62.
Nineteen patients with polycystic ovarian disease (PCO) underwent ultrasound examinations. Criteria of PCO were determined by clinical findings [(1) sterility (2) irregular menses], and hormonal analysis [(1) basal LH level greater than or equal to 20 mIU/ml, (2) LH/FSH greater than or equal to 2.5, (3) maximum LH level after LH-RH test greater than or equal to 150 mIU/ml]. Seven cases out of nineteen patients were confirmed by histologic examinations. Fourteen normal women were compared with PCO patients. We have obtained the following results. No significant differences between PCO groups and normal women were observed in uterine longest diameter (ULD) and uterine volume (UV). On the other hand, correlation tests of ovarian longest diameter (OLD), ovarian volume (OV), OLD/ULD and OV/UV were highly significant (p less than 0.01), as compared with each for normal women. The sonographic spectra of ovarian morphology in PCO were classified into three types. In type I, the ovary was filled with a light homogeneous echo. And type II was divided into two small types, IIa and IIb. In type IIa, small cysts (3-5 mm) were sporadic in the ovary and indistinct. In type IIb, the cyst was rather larger (5-7 mm) and more distinct than that of type IIa. In type III, the capsule echo of the ovary was thick and cysts under the capsule were 3-7 mm-sized and arranged regularly. We investigated the induced ovulation rates with clomiphene in each type. Two of 4 cases of type I and 6 of 8 cases of type IIa were induced.(ABSTRACT TRUNCATED AT 250 WORDS)
19例多囊卵巢疾病(PCO)患者接受了超声检查。PCO的诊断标准由临床症状[(1)不孕(2)月经不规律]及激素分析[(1)基础促黄体生成素(LH)水平≥20 mIU/ml,(2)LH/促卵泡生成素(FSH)≥2.5,(3)LH释放激素(LH-RH)试验后LH最高水平≥150 mIU/ml]确定。19例患者中有7例经组织学检查确诊。将14名正常女性与PCO患者进行比较。我们得到了以下结果。PCO组与正常女性在子宫最长径(ULD)和子宫体积(UV)方面未观察到显著差异。另一方面,与正常女性各自相比,卵巢最长径(OLD)、卵巢体积(OV)、OLD/ULD及OV/UV的相关性检验具有高度显著性(p<0.01)。PCO患者卵巢形态的超声图像谱分为三种类型。I型中,卵巢充满均匀低回声。II型分为两个小类,IIa和IIb。IIa型中,小囊肿(3 - 5毫米)散在分布于卵巢且不清晰。IIb型中,囊肿比IIa型更大(5 - 7毫米)且更清晰。III型中,卵巢包膜回声增厚,包膜下囊肿大小为3 - 7毫米且排列规则。我们研究了每种类型患者使用克罗米芬诱导排卵的成功率。I型4例中有2例、IIa型8例中有6例成功诱导排卵。(摘要截断于250字)