Department of Pharmacy, NYU Langone Health, New York, NY, USA.
Department of Medicine, NYU Langone Health, New York, NY, USA.
J Pharm Pract. 2023 Oct;36(5):1156-1163. doi: 10.1177/08971900221091174. Epub 2022 Apr 24.
Medication reconciliation is the process of comparing a patient's hospital medication orders to all of the medications that the patient has been taking prior to admission. The primary aim of this study was to evaluate the effectiveness of pharmacist-led medication reconciliation in reducing ED visit rates. The secondary aim of this study was to evaluate if a clinical pharmacist reduces medication errors in an ED observation unit (OBS). This was a retrospective, IRB approved, chart review conducted at New York University Langone Health-Tisch Hospital. The study defines the year before a clinical pharmacist was present on the unit (July 5, 2016 through July 4, 2017) as the control group and the first year a clinical pharmacist was present on the unit (July 5, 2017 through July 4, 2018) as the intervention group. The primary endpoint was 30-day ED re-visits. The secondary endpoints were 60-and 90-day ED re-visits, number, type and severity of medication history and reconciliation discrepancies. The primary endpoint of 30-day ED visits occurred in 153 patients in the no pharmacist group and 88 patients in the OBS clinical pharmacist group (19.1% vs 9.9%, P < .00001). The secondary endpoint of 60- day ED visits occurred in 53 patients in the no pharmacist group and 39 patients in the OBS clinical pharmacist group (8.2% vs 4.9%, P = .01). The secondary endpoint of 90- day ED visits occurred in 31 patients in the no pharmacist group and 26 patients in the OBS clinical pharmacist group (5.2% vs 3.4%, P = .01). The benefits of having a clinical pharmacist perform medication reconciliation are highlighted by the reduction in ED visits, cost savings, and the prolific amount of errors corrected.
药物重整是比较患者的住院药物医嘱与患者入院前服用的所有药物的过程。本研究的主要目的是评估药剂师主导的药物重整在降低 ED 就诊率方面的有效性。本研究的次要目的是评估临床药师是否可以减少 ED 观察单元(OBS)中的药物错误。这是一项回顾性、经 IRB 批准的图表审查,在纽约大学朗格尼健康-蒂施医院进行。该研究将临床药师到岗前的一年(2016 年 7 月 5 日至 2017 年 7 月 4 日)定义为对照组,将临床药师到岗后的第一年(2017 年 7 月 5 日至 2018 年 7 月 4 日)定义为干预组。主要终点为 30 天内 ED 再就诊。次要终点为 60 天和 90 天内 ED 再就诊、药物史和重整差异的数量、类型和严重程度。无药师组的 30 天 ED 就诊主要终点为 153 例患者,OBS 临床药师组为 88 例患者(19.1%比 9.9%,P<.00001)。无药师组的 60 天 ED 就诊次要终点为 53 例患者,OBS 临床药师组为 39 例患者(8.2%比 4.9%,P=0.01)。无药师组的 90 天 ED 就诊次要终点为 31 例患者,OBS 临床药师组为 26 例患者(5.2%比 3.4%,P=0.01)。临床药师进行药物重整的好处在于降低了 ED 就诊率、节省了成本,并纠正了大量的错误。