Friedman W A, Grundy B L
J Clin Monit. 1987 Jan;3(1):38-44. doi: 10.1007/BF00770882.
Because short-latency evoked potentials are relatively resistant to anesthetic agents, they can be used to monitor neural pathways during surgical procedures. The use of median nerve somatosensory evoked potentials to localize the central sulcus is an established aid of indisputable value in neurosurgical procedures involving cortical incisions for resection of certain epileptic foci, vascular malformations, or neoplasms near the central area of the brain. Likewise, recording of intraoperative nerve action potentials is currently regarded as indispensable in management of the neuroma-incontinuity after peripheral nerve trauma, as this evoked potential monitoring technique provides the only reliable method of distinguishing between axonotmetic and neurotmetic lesions. Evoked potential monitoring has been of value during many other types of surgical procedures, including cerebral aneurysm clipping, carotid endarterectomy, aortic procedures, microvascular decompression for trigeminal neuralgia and hemifacial spasm, acoustic neuroma resection, and a variety of spinal procedures. A detailed review of the literature is presented on the use of evoked potential monitoring for one of the more common indications: scoliosis surgery. Many orthopedic surgeons use the "wake-up test" only if the somatosensory evoked potentials change during surgery. A detailed review of the few reported cases of "false negative" evoked potentials is presented. The dearth of convincing reports of such phenomena in the face of so many positive experiences should persuade even the skeptical that monitoring of evoked potentials is a highly reliable and helpful intraoperative tool.
由于短潜伏期诱发电位对麻醉剂相对不敏感,因此可用于在手术过程中监测神经通路。在涉及切除某些癫痫病灶、血管畸形或大脑中央区域附近肿瘤的皮质切开术的神经外科手术中,使用正中神经体感诱发电位来定位中央沟是一种具有无可争议价值的既定辅助手段。同样,术中记录神经动作电位目前被认为是处理周围神经损伤后连续性神经瘤不可或缺的方法,因为这种诱发电位监测技术是区分轴突断裂和神经断裂损伤的唯一可靠方法。诱发电位监测在许多其他类型的手术过程中也具有价值,包括脑动脉瘤夹闭术、颈动脉内膜切除术、主动脉手术、三叉神经痛和半面痉挛的微血管减压术、听神经瘤切除术以及各种脊柱手术。本文对诱发电位监测在较常见的适应症之一:脊柱侧弯手术中的应用进行了详细的文献综述。许多骨科医生仅在手术过程中体感诱发电位发生变化时才使用“唤醒试验”。本文对少数报道的“假阴性”诱发电位病例进行了详细综述。面对如此多的积极经验,关于此类现象的令人信服的报告却很少,这甚至应该能说服持怀疑态度的人相信,诱发电位监测是一种高度可靠且有用的术中工具。