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耻骨后根治性前列腺切除术前行计算机断层扫描和经直肠超声评估前列腺癌局部浸润情况

Computerized tomography and transrectal ultrasound in the assessment of local extension of prostatic cancer before radical retropubic prostatectomy.

作者信息

Salo J O, Kivisaari L, Rannikko S, Lehtonen T

出版信息

J Urol. 1987 Mar;137(3):435-8. doi: 10.1016/s0022-5347(17)44059-6.

DOI:10.1016/s0022-5347(17)44059-6
PMID:3546732
Abstract

The value of computerized tomography and transrectal ultrasound in the demonstration of local extension of prostatic cancer was evaluated in 38 patients undergoing radical retropubic prostatectomy. Transrectal ultrasound proved to be reliable for the demonstration of local extension of cancer beyond the prostatic capsule (sensitivity 86 per cent, specificity 94 per cent and accuracy 90 per cent). Invasion of the seminal vesicles was demonstrated by ultrasound, with a sensitivity of 29 per cent, specificity 100 per cent and accuracy 77 per cent. The addition of transrectal ultrasound scanning to clinical evaluation increased sensitivity in relation to detection of extraprostatic involvement from 15 to 92 per cent. When computerized tomography scanning was added to clinical examination, the sensitivity increased from 15 to only 46 per cent. Transrectal ultrasound is valuable for the preoperative evaluation of patients in whom radical prostatectomy is being considered as treatment for clinically localized prostatic cancer.

摘要

对38例接受耻骨后根治性前列腺切除术的患者,评估了计算机断层扫描和经直肠超声在显示前列腺癌局部扩散方面的价值。经直肠超声被证明在显示癌超出前列腺包膜的局部扩散方面可靠(敏感性86%,特异性94%,准确性90%)。超声显示精囊受侵,敏感性为29%,特异性100%,准确性77%。经直肠超声扫描加入临床评估后,检测前列腺外受累的敏感性从15%提高到92%。当计算机断层扫描加入临床检查时,敏感性仅从15%提高到46%。经直肠超声对考虑将根治性前列腺切除术作为临床局限性前列腺癌治疗方法的患者的术前评估有价值。

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The effectiveness of imaging modalities in clinical staging of localized prostatic carcinoma.
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Identification of the human prostatic carcinoma oncogene PTI-1 by rapid expression cloning and differential RNA display.通过快速表达克隆和差异RNA显示鉴定人类前列腺癌致癌基因PTI-1。
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