Francis D P, Chin J
JAMA. 1987 Mar 13;257(10):1357-66.
Human immunodeficiency virus (HIV) is one of the most virulent infectious agents ever encountered. This virus, estimated to kill up to a half of those infected, has spread to more than 1 million Americans. There is no safe and effective treatment. Nor is there a vaccine. From our understanding of HIV transmission, further spread of the virus can be stopped by the use of various techniques. The combined use of education-motivation-skill building, serologic screening, and contact tracing/notification could eliminate or substantially reduce transmission. To accomplish this reduction an immense concerted effort by physicians, public health practitioners, business, and community organizations is required to get across the simple prevention messages. Those messages are: Any sexual intercourse (outside of mutually monogamous or HIV antibody-negative relationships) must be protected with a condom. Do not share unsterile needles or syringes. All women who may have been exposed should seek HIV-antibody testing before becoming pregnant and, if positive, avoid pregnancy. Only through a concerted, vigorous, and sustained prevention program that deals frankly with this problem will those individuals at risk be reached and motivated to take personal responsibility to protect themselves. Without such an effort, acquired immunodeficiency syndrome will continue to kill ever-increasing numbers of Americans.
人类免疫缺陷病毒(HIV)是迄今发现的毒性最强的传染因子之一。据估计,这种病毒会导致多达一半的感染者死亡,目前已传播至100多万美国人。既没有安全有效的治疗方法,也没有疫苗。根据我们对HIV传播的了解,运用各种技术可以阻止病毒的进一步传播。将教育-激励-技能培养、血清学筛查以及接触者追踪/通知结合起来使用,能够消除或大幅减少传播。为了实现这种传播的减少,医生、公共卫生从业者、企业和社区组织需要做出巨大的协同努力,以传达这些简单的预防信息。这些信息是:任何性行为(相互一夫一妻制关系或HIV抗体阴性关系之外)都必须使用避孕套进行保护。不要共用未经消毒的针头或注射器。所有可能接触过病毒的女性在怀孕前都应进行HIV抗体检测,如果检测呈阳性,则应避免怀孕。只有通过一个坦率应对这一问题的协同、有力且持续的预防计划,才能让那些有风险的人了解情况并促使他们为保护自己承担个人责任。如果不做出这样的努力,获得性免疫缺陷综合征将继续导致越来越多的美国人死亡。