Abildskov J A
Jpn Heart J. 1986 Nov;27 Suppl 1:197-204.
The ventricular gradient concept of Wilson was an important insight into the physiology of ventricular repolarization and its electrocardiographic expression. For many years the validity of the concept was questioned because QRST deflection area was not independent of ventricular activation sequence but it is now evident that electrotonic effects on repolarization account for that behavior. There is solid theoretic and experimental evidence that QRST deflection area depends on disparity of repolarization. The established relation of disparate repolarization to arrhythmia vulnerability provides an important clinical objective for measurement of the QRST area and promising evidence for the prediction of arrhythmias has been obtained. Finally, there is evidence that the sufficiently sampled map of QRST deflection areas provides useful information concerning the distribution of repolarization properties as well as their disparity.
威尔逊的心室梯度概念是对心室复极化生理学及其心电图表现的一项重要见解。多年来，该概念的有效性受到质疑，因为QRST波的偏转面积并非独立于心室激动顺序，但现在很明显，复极化的电紧张效应可以解释这种现象。有确凿的理论和实验证据表明，QRST波的偏转面积取决于复极化的差异。复极化差异与心律失常易感性之间已确立的关系为测量QRST面积提供了一个重要的临床目标，并且已经获得了有关心律失常预测的有前景的证据。最后，有证据表明，对QRST偏转面积进行充分采样的图谱可提供有关复极化特性分布及其差异的有用信息。
