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SPECT-MPI 显示非优势右冠状动脉和非显著冠状动脉疾病患者下壁心肌缺血。

Inferior myocardial wall ischemia on SPECT-MPI in patients with non dominant right coronary artery and non significant coronary artery disease.

机构信息

Department of Cardiology, Patras University Hospital, Rion, Patras, Greece.

Laboratory of Nuclear Medicine, University Hospital, Rion, Patras, Greece.

出版信息

Int J Cardiol. 2022 Jul 1;358:8-10. doi: 10.1016/j.ijcard.2022.04.058. Epub 2022 Apr 23.

Abstract

BACKGROUND

The impact of a non-dominant right coronary artery (NDRCA), on single photon emission computed tomography (SPECT) myocardial perfusion imaging (MPI)has not been clarified.

METHODS AND RESULTS

We compared SPECT-MPI results of consecutive patients without significant (diameter stenosis ≥50%)coronary artery disease (CAD) and a NDRCA (Group-1), with those of patients from our database without CAD and a dominant RCA (Group-2). All patients were subjected to SPECT-MPI with I.V. infusion of adenosine, and TC-tetrofosmin. Group-1 included 69 patients (55 men, 79.7%), mean age 66.8 ± 9.8 years. Group-2 consisted of 79 patients (56 men, 70.9%), mean age 62.7 ± 11.5. There was no difference in demographics and CAD risk factors between the two groups. The SPECT-MPI revealed inferior wall ischemia, in 35 patients (50.7%), in Group-1 and 27 patients (34.1%), in Group-2 (P = 0.041).

CONCLUSIONS

A relatively high rate of reversible SPECT-MPI perfusion defects may be anticipated in patients with an unobstructed NDRCA compared to patients with a dominant RCA.

摘要

背景

非优势右冠状动脉(NDRCA)对单光子发射计算机断层扫描(SPECT)心肌灌注成像(MPI)的影响尚未明确。

方法和结果

我们比较了连续无明显(直径狭窄≥50%)冠心病(CAD)且存在 NDRCA 的患者(组 1)与我们数据库中无 CAD 且优势 RCA 存在的患者(组 2)的 SPECT-MPI 结果。所有患者均接受静脉注射腺苷和 TC-四氟甲基磷的 SPECT-MPI。组 1 包括 69 例患者(55 名男性,79.7%),平均年龄 66.8±9.8 岁。组 2 由 79 例患者(56 名男性,70.9%)组成,平均年龄 62.7±11.5 岁。两组间的人口统计学和 CAD 危险因素无差异。SPECT-MPI 显示,组 1 中有 35 例(50.7%)下壁缺血,组 2 中有 27 例(34.1%)(P=0.041)。

结论

与优势 RCA 患者相比,无阻塞性 NDRCA 患者的 SPECT-MPI 灌注缺陷可逆性较高。

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