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基于强度的迭代重建在静态光栅配置螺旋光栅干涉乳腺 CT 中的应用。

Intensity-based iterative reconstruction for helical grating interferometry breast CT with static grating configuration.

出版信息

Opt Express. 2022 Apr 11;30(8):13847-13863. doi: 10.1364/OE.455967.

Abstract

Grating interferometry breast computed tomography (GI-BCT) has the potential to provide enhanced soft tissue contrast and to improve visualization of cancerous lesions for breast imaging. However, with a conventional scanning protocol, a GI-BCT scan requires longer scanning time and higher operation complexity compared to conventional attenuation-based CT. This is mainly due to multiple grating movements at every projection angle, so-called phase stepping, which is used to retrieve attenuation, phase, and scattering (dark-field) signals. To reduce the measurement time and complexity and extend the field of view, we have adopted a helical GI-CT setup and present here the corresponding tomographic reconstruction algorithm. This method allows simultaneous reconstruction of attenuation, phase contrast, and scattering images while avoiding grating movements. Experiments on simulated phantom and real initial intensity, visibility and phase maps are provided to validate our method.

摘要

光栅干涉断层成像乳腺计算机断层扫描(GI-BCT)有可能提供增强的软组织对比度,并改善乳腺癌成像的癌性病变的可视化。然而,与传统基于衰减的 CT 相比,使用常规扫描方案时,GI-BCT 扫描需要更长的扫描时间和更高的操作复杂性。这主要是由于在每个投影角度(所谓的相位步进)都需要多次光栅移动,以获取衰减、相位和散射(暗场)信号。为了减少测量时间和复杂性并扩展视场,我们采用了螺旋 GI-CT 设置,并在此介绍了相应的层析重建算法。该方法允许同时重建衰减、相位对比和散射图像,同时避免光栅运动。提供了模拟体模和真实初始强度、可见度和相位图的实验,以验证我们的方法。

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