Larson J L, Kim M J
Nurs Clin North Am. 1987 Mar;22(1):207-23.
In brief, preliminary research suggests that respiratory muscle fatigue contributes to the clinical manifestations of CAL and is associated with changes in breathing patterns. The specific mechanisms for changes in breathing patterns have not been clearly elucidated. Moreover, the mechanisms of respiratory muscle fatigue remain unclear, and clinical methods for diagnosing respiratory muscle fatigue are inconclusive. Until we improve our understanding of respiratory muscle fatigue, interventions are mostly directed toward preventing respiratory muscle fatigue by improving respiratory muscle function. One way to achieve this goal is by inspiratory muscle training. However, further research is needed to elucidate the physiologic mechanisms, clinical implications, and therapeutic interventions for respiratory muscle fatigue so that we can improve the associated ineffective breathing patterns.
简而言之，初步研究表明呼吸肌疲劳会导致慢性阻塞性肺疾病（CAL）的临床表现，并与呼吸模式的改变有关。呼吸模式改变的具体机制尚未明确阐明。此外，呼吸肌疲劳的机制仍不清楚，诊断呼吸肌疲劳的临床方法也尚无定论。在我们更好地理解呼吸肌疲劳之前，干预措施大多旨在通过改善呼吸肌功能来预防呼吸肌疲劳。实现这一目标的一种方法是进行吸气肌训练。然而，需要进一步研究以阐明呼吸肌疲劳的生理机制、临床意义和治疗干预措施，以便我们能够改善相关的无效呼吸模式。
