Vrettos Apostolos, Duncan Alison, Ahmed Asrar, Heng Ee Ling, Panoulas Vasileios
Department of Cardiology, Royal Brompton & Harefield Hospitals, Guy's and St Thomas' NHS Foundation Trust, Hill End Rd, Harefield, Uxbridge UB9 6JH, UK.
Faculty of Medicine, Cardiovascular Sciences, National Heart and Lung Institute, Imperial College London, Royal Brompton Campus, Guy Scadding Building, Cale Street, London SW3 6LY, UK.
Eur Heart J Case Rep. 2022 Feb 22;6(3):ytac094. doi: 10.1093/ehjcr/ytac094. eCollection 2022 Mar.
Aortic-to-right ventricle (ARV) fistula is an uncommon complication of transcatheter aortic valve implantation (TAVI). Even though surgical closure is usually the treatment of choice in such communications, percutaneous treatment options are valuable alternatives for these high-risk surgical patients.
In this article, we present the percutaneous closure of an ARV fistula after TAVI, in a highly symptomatic patient with recurrent episodes of heart failure decompensation with worsening right ventricular function, who failed conservative medical treatment and was deemed inoperable. Successful closure of the fistula with the use of the Amplatzer atrial septal occluder was performed 6 months post-TAVI, under general anaesthesia and transoesophageal echocardiography (TOE). A detailed multi-modality imaging pre-procedural planning was performed utilizing 4D cardiac computed tomography and echocardiography. The patient has remained asymptomatic and in good health 5 months after the ARV fistula closure, with marked improvement in his clinical picture and echocardiographic parameters.
Aortic-to-right ventricle fistulas with significant shunt post-TAVI could lead to biventricular failure and are associated with increased mortality if left untreated. This case demonstrates that TOE-guided percutaneous closure of a TAVI-related ARV fistula, although technically challenging, is feasible, and can be a valuable option for the treatment of symptomatic high-risk surgical patients.
主动脉-右心室(ARV)瘘是经导管主动脉瓣植入术(TAVI)的一种罕见并发症。尽管手术闭合通常是此类交通的首选治疗方法,但对于这些高风险手术患者,经皮治疗选择是有价值的替代方案。
在本文中,我们介绍了一名TAVI术后ARV瘘的经皮闭合病例。该患者症状严重,反复出现心力衰竭失代偿发作,右心室功能恶化,保守药物治疗失败且被认为无法进行手术。在全身麻醉和经食管超声心动图(TOE)引导下,于TAVI术后6个月使用Amplatzer房间隔封堵器成功闭合了瘘管。术前利用4D心脏计算机断层扫描和超声心动图进行了详细的多模态成像规划。ARV瘘管闭合5个月后,患者一直无症状且健康状况良好,临床症状和超声心动图参数有明显改善。
TAVI术后伴有明显分流的主动脉-右心室瘘可导致双心室衰竭,若不治疗,死亡率会增加。该病例表明,TOE引导下经皮闭合TAVI相关的ARV瘘管虽然在技术上具有挑战性,但却是可行的,对于有症状的高风险手术患者来说可能是一种有价值的治疗选择。