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颅内动脉瘤的血管内母动脉闭塞术是一种可行且具有成本效益的替代方案:来自印度东北部的机构经验。

Endovascular Parent Artery Occlusion for Intracranial Aneurysms is a Viable, Cost-Effective Alternative: An Institutional Experience from Northeast India.

作者信息

Phukan Pranjal, Samra Kalyan, Lynser Donboklang, Sharma Barun Kumar, Boruah Deb Kumar, Saikia Bishwaeet, Singh Binoy Kumar

机构信息

Department of Radiology & ImagingNorth Eastern Indira Gandhi Regional Institute of Health & Medical Sciences, Meghalaya, India.

Department of Neuroimaging & Interventional Neuroradiology All India Institute of Medical Science, New Delhi.

出版信息

Acta Med Litu. 2021;28(2):272-284. doi: 10.15388/Amed.2021.28.2.6. Epub 2021 Aug 4.

Abstract

PURPOSE

Endovascular parent artery occlusion (PAO) may be an alternative approach for complex intracranial aneurysm with potentially life-threatening complications. Moreover, the long-term follow-up of the PAO for an intracranial aneurysm is reported sparingly, limited to the case series. It is therefore important to carry out more research on long-term follow-up of the implication of PAO of intracranial aneurysm. The aim of the study was to analyses our experience of PAO for intracranial aneurysms with emphasis on long-term follow-up.

MATERIALS AND METHODS

The data of patients treated with PAO for intracranial aneurysms were reviewed. The outcome was evaluated based on aneurysmal occlusion on immediate angiography, follow-up magnetic resonance angiography (MRA), and complications. The modified Rankin score (mRS) was used to evaluate the functional outcome during the last follow-up. The mean, range, and standard deviation were reported for other variables - the patient's age, number, and percentage.

RESULTS

Endovascular treatment was performed in 178 patients including PAO in 18 patients. Of these 18 (eighteen) patients, there were 13 dissecting aneurysms, 4 mycotic aneurysms, and one traumatic aneurysm.10 (ten) patients underwent PAO for proximal intracranial artery aneurysm and 8 (eight) patients for distal cerebral aneurysms. Complete occlusion of the aneurysm was achieved in 16patients (88.89%) and retrograde filling of the aneurysm was seen in 2 (11.11%) patients. One patient had intraprocedural coil migration resulting in a major infarct with an mRS of 2. Another patient (5.56%) had recanalization of the aneurysm and presented with rupture and intracranial hemorrhage with an mRS score of 4. The mRS of the other 16 patients (88.89%) was zero.

CONCLUSIONS

Endovascular PAO for cerebral aneurysms was highly feasible and achieved complete occlusion. The morbidity and mortality rates were at the long-term follow-up also acceptable with negligible complications.

摘要

目的

血管内载瘤动脉闭塞术(PAO)可能是治疗复杂颅内动脉瘤的一种替代方法,这类动脉瘤可能会引发危及生命的并发症。此外,关于颅内动脉瘤PAO的长期随访报道较少,仅限于病例系列研究。因此,对颅内动脉瘤PAO的长期随访意义开展更多研究很重要。本研究的目的是分析我们在颅内动脉瘤PAO方面的经验,重点是长期随访。

材料与方法

回顾了接受颅内动脉瘤PAO治疗的患者数据。根据即刻血管造影、随访磁共振血管造影(MRA)上的动脉瘤闭塞情况以及并发症来评估结果。采用改良Rankin量表(mRS)评估末次随访时的功能结局。报告其他变量(患者年龄、数量及百分比)的均值、范围和标准差。

结果

178例患者接受了血管内治疗,其中18例接受了PAO。在这18例患者中,有13例夹层动脉瘤、4例感染性动脉瘤和1例创伤性动脉瘤。10例患者因颅内近端动脉动脉瘤接受PAO,8例患者因大脑远端动脉瘤接受PAO。16例患者(88.89%)实现了动脉瘤完全闭塞,2例患者(11.11%)可见动脉瘤逆行充盈。1例患者术中出现弹簧圈移位,导致大面积梗死,mRS评分为2分。另1例患者(5.56%)动脉瘤再通,出现破裂和颅内出血,mRS评分为4分。其他16例患者(88.89%)的mRS评分为0分。

结论

颅内动脉瘤的血管内PAO高度可行,且实现了完全闭塞。长期随访时的发病率和死亡率也可接受,并发症极少。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/35bd/8958658/2d3b5b716e74/aml-28-272-g001.jpg

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