Phukan Pranjal, Samra Kalyan, Lynser Donboklang, Sharma Barun Kumar, Boruah Deb Kumar, Saikia Bishwaeet, Singh Binoy Kumar
Department of Radiology & ImagingNorth Eastern Indira Gandhi Regional Institute of Health & Medical Sciences, Meghalaya, India.
Department of Neuroimaging & Interventional Neuroradiology All India Institute of Medical Science, New Delhi.
Acta Med Litu. 2021;28(2):272-284. doi: 10.15388/Amed.2021.28.2.6. Epub 2021 Aug 4.
Endovascular parent artery occlusion (PAO) may be an alternative approach for complex intracranial aneurysm with potentially life-threatening complications. Moreover, the long-term follow-up of the PAO for an intracranial aneurysm is reported sparingly, limited to the case series. It is therefore important to carry out more research on long-term follow-up of the implication of PAO of intracranial aneurysm. The aim of the study was to analyses our experience of PAO for intracranial aneurysms with emphasis on long-term follow-up.
The data of patients treated with PAO for intracranial aneurysms were reviewed. The outcome was evaluated based on aneurysmal occlusion on immediate angiography, follow-up magnetic resonance angiography (MRA), and complications. The modified Rankin score (mRS) was used to evaluate the functional outcome during the last follow-up. The mean, range, and standard deviation were reported for other variables - the patient's age, number, and percentage.
Endovascular treatment was performed in 178 patients including PAO in 18 patients. Of these 18 (eighteen) patients, there were 13 dissecting aneurysms, 4 mycotic aneurysms, and one traumatic aneurysm.10 (ten) patients underwent PAO for proximal intracranial artery aneurysm and 8 (eight) patients for distal cerebral aneurysms. Complete occlusion of the aneurysm was achieved in 16patients (88.89%) and retrograde filling of the aneurysm was seen in 2 (11.11%) patients. One patient had intraprocedural coil migration resulting in a major infarct with an mRS of 2. Another patient (5.56%) had recanalization of the aneurysm and presented with rupture and intracranial hemorrhage with an mRS score of 4. The mRS of the other 16 patients (88.89%) was zero.
Endovascular PAO for cerebral aneurysms was highly feasible and achieved complete occlusion. The morbidity and mortality rates were at the long-term follow-up also acceptable with negligible complications.
血管内载瘤动脉闭塞术(PAO)可能是治疗复杂颅内动脉瘤的一种替代方法,这类动脉瘤可能会引发危及生命的并发症。此外,关于颅内动脉瘤PAO的长期随访报道较少,仅限于病例系列研究。因此,对颅内动脉瘤PAO的长期随访意义开展更多研究很重要。本研究的目的是分析我们在颅内动脉瘤PAO方面的经验,重点是长期随访。
回顾了接受颅内动脉瘤PAO治疗的患者数据。根据即刻血管造影、随访磁共振血管造影(MRA)上的动脉瘤闭塞情况以及并发症来评估结果。采用改良Rankin量表(mRS)评估末次随访时的功能结局。报告其他变量(患者年龄、数量及百分比)的均值、范围和标准差。
178例患者接受了血管内治疗,其中18例接受了PAO。在这18例患者中,有13例夹层动脉瘤、4例感染性动脉瘤和1例创伤性动脉瘤。10例患者因颅内近端动脉动脉瘤接受PAO,8例患者因大脑远端动脉瘤接受PAO。16例患者(88.89%)实现了动脉瘤完全闭塞,2例患者(11.11%)可见动脉瘤逆行充盈。1例患者术中出现弹簧圈移位,导致大面积梗死,mRS评分为2分。另1例患者(5.56%)动脉瘤再通,出现破裂和颅内出血,mRS评分为4分。其他16例患者(88.89%)的mRS评分为0分。
颅内动脉瘤的血管内PAO高度可行,且实现了完全闭塞。长期随访时的发病率和死亡率也可接受,并发症极少。