Alexander D L, Lin C H
Prostaglandins. 1986 Nov;32(5):647-53. doi: 10.1016/0090-6980(86)90187-5.
Two new diastereomeric benzindene prostacyclin analogs (U-72,382 and U-72,383) related to the potent antiulcer agent U-68,215 have been synthesized. These cyclohexyl ring modified analogs of U-68,215 were prepared to determine how the gastrointestinal and hypotensive endpoints observed for U-68,215 would be affected.
已合成了两种与强效抗溃疡剂U-68,215相关的非对映异构苯茚前列环素类似物（U-72,382和U-72,383）。制备这些U-68,215的环己基环修饰类似物是为了确定观察到的U-68,215的胃肠道和降压终点将如何受到影响。
