Lejman K, Starzycki Z
Br J Vener Dis. 1978 Aug;54(4):278-82. doi: 10.1136/sti.54.4.278.
Malignant syphilitic infections occurring in the same woman at an interval of 38 months is reported. The first infection was diagnosed as secondary papulopustular and ecthymatous syphilis. The reinfection was more severe, taking the form of secondary ulcerative syphilis with fever, general deterioration, and loss of weight. Numerous Treponema pallidum were present in the serum expressed from the papulopustular lesions during the first infection, but they were absent from the secretion expressed from the margins of the ulcerative symphilides during the reinfection. Many treponemes were present in the plasma cell infiltrates in histopathological sections of the biopsy specimens taken from the margin of the ulcers.
据报道，同一女性在间隔38个月时发生了恶性梅毒感染。首次感染被诊断为二期丘疹脓疱性及深脓疱性梅毒。再次感染更为严重，表现为二期溃疡性梅毒，伴有发热、全身状况恶化和体重减轻。首次感染时，丘疹脓疱性损害分泌的血清中有大量梅毒螺旋体，但再次感染时，溃疡性梅毒损害边缘的分泌物中未发现梅毒螺旋体。从溃疡边缘获取的活检标本的组织病理学切片中，浆细胞浸润处存在许多梅毒螺旋体。
