Zhao Xiaohuan, Liu Wenjia, Lu Bing, Zhu Xinyue, Zhou Minwen, Sun Xiaodong
Department of Ophthalmology, Shanghai General Hospital (Shanghai First People's Hospital), Shanghai Jiao Tong University School of Medicine, Shanghai, China.
National Clinical Research Center for Eye Diseases, Shanghai, China.
BMJ Open. 2022 Apr 27;12(4):e055563. doi: 10.1136/bmjopen-2021-055563.
To explore the longitudinal association between visual impairment (VI) and depression among adults 45 years and older in China based on a nationally representative follow-up dataset.
Participants in China from the China Health and Retirement Longitudinal Study were included.
A total of 6748 participants from two waves of the China Health and Retirement Longitudinal Study 2011-2018 were included for analysis by age group.
VI and depression were defined by self-diagnosis and the Center for Epidemiological Studies Depression Scale-10, respectively. Lagged dependent variable regression models with ordinary least squares estimation were used to evaluate the association between VI and depression. Age was divided into three groups, that is, 45-54, 55-64, and 65 years and older, to explore the relationship between VI and depression in different age groups.
In our study sample, VI remarkably predicted an increase in depressive scores. The magnitude of depressive scores increased among those with VI points greater than 3.517 (β=3.517; 95% CI=2.697 to 4.331) points than those without VI in the 7-year follow-up. Significant relationships were also found between VI and depression in the three age groups in the sensitivity analysis.
VI was associated with an increase in depression scores over a 7-year period. Female respondents, low educational attainment and high alcohol intake significantly predicted an increase in depressive status.
基于具有全国代表性的随访数据集,探讨中国45岁及以上成年人视力障碍(VI)与抑郁症之间的纵向关联。
纳入中国健康与养老追踪调查(China Health and Retirement Longitudinal Study)的中国参与者。
来自2011 - 2018年中国健康与养老追踪调查两期的6748名参与者按年龄组纳入分析。
视力障碍和抑郁症分别通过自我诊断和流行病学研究中心抑郁量表 - 10进行定义。采用普通最小二乘法估计的滞后因变量回归模型来评估视力障碍与抑郁症之间的关联。年龄分为三组,即45 - 54岁、55 - 64岁和65岁及以上,以探讨不同年龄组中视力障碍与抑郁症之间的关系。
在我们的研究样本中,视力障碍显著预测了抑郁评分的增加。在7年随访中,视力障碍得分大于3.517(β = 3.517;95%置信区间 = 2.697至4.331)分的人群,其抑郁评分的增幅高于无视力障碍者。敏感性分析中还发现三个年龄组的视力障碍与抑郁症之间存在显著关系。
在7年期间,视力障碍与抑郁评分增加相关。女性受访者、低教育程度和高酒精摄入量显著预测了抑郁状态的增加。