Wu Xiaochen, Guo Zhao, Zhu Shuang, Zhang Bingbing, Guo Sumin, Dong Xinghua, Mei Linqiang, Liu Ruixue, Su Chunjian, Gu Zhanjun
CAS Key Laboratory for Biomedical Effects of Nanomaterials and Nanosafety and CAS Center for Excellence in Nanoscience, Institute of High Energy Physics and National Center for Nanoscience and Technology, Chinese Academy of Sciences, Beijing, 100049, China.
College of Mechanical and Electronic Engineering, Shandong University of Science and Technology, Qingdao, 266590, China.
Adv Sci (Weinh). 2022 Jun;9(17):e2200831. doi: 10.1002/advs.202200831. Epub 2022 Apr 28.
Inorganic perovskite quantum dots CsPbX (X = Cl, Br, and I) has recently received extensive attention as a new promising class of X-ray scintillators. However, relatively low light yield (LY) of CsPbX and strong optical scattering of the thick opaque scintillator film restrict their practical applications for high-resolution X-ray microscopic imaging. Here, the Ce ion doped CsPbBr nanocrystals (NCs) with enhanced LY and stability are obtained and then the ultrathin (30 µm) and transparent scintillator films with high density are prepared by a suction filtration method. The small amount Ce dopant greatly enhances the LY of CsPbBr NCs (about 33 000 photons per MeV), which is much higher than that of bare CsPbBr NCs. Moreover, the scintillator films made by these NCs with high density realize a high spatial resolution of 862 nm thanks to its thin and transparent feature, which is so far a record resolution for perovskite scintillator-based X-ray microscopic imaging. This strategy not only provides a simple way to increase the resolution down to nanoscale but also extends the application of as-prepared CsPbBr scintillator for high resolution X-ray microscopic imaging.
无机钙钛矿量子点CsPbX（X = Cl、Br和I）作为一类新型有前景的X射线闪烁体最近受到了广泛关注。然而，CsPbX相对较低的光产额（LY）以及厚的不透明闪烁体膜的强光学散射限制了它们在高分辨率X射线显微成像中的实际应用。在此，获得了具有增强的光产额和稳定性的Ce离子掺杂CsPbBr纳米晶体（NCs），然后通过抽滤法制备了具有高密度的超薄（30 µm）透明闪烁体膜。少量的Ce掺杂剂极大地提高了CsPbBr NCs的光产额（约每兆电子伏特33000个光子），这远高于纯CsPbBr NCs的光产额。此外，由这些具有高密度的NCs制成的闪烁体膜由于其薄且透明的特性实现了862 nm的高空间分辨率，这是迄今为止基于钙钛矿闪烁体的X射线显微成像的记录分辨率。该策略不仅提供了一种将分辨率降低到纳米级的简单方法，还扩展了所制备的CsPbBr闪烁体在高分辨率X射线显微成像中的应用。
