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由药剂师主导,为无家可归者提供艾滋病毒和丙型肝炎即时检测及风险缓解咨询服务。

Pharmacist-led HIV and hepatitis C point-of-care testing and risk mitigation counseling in individuals experiencing homelessness.

作者信息

Kherghehpoush Sorosh, McKeirnan Kimberly C

机构信息

Washington State University College of Pharmacy and Pharmaceutical Sciences, USA.

出版信息

Explor Res Clin Soc Pharm. 2021 Apr 5;1:100007. doi: 10.1016/j.rcsop.2021.100007. eCollection 2021 Mar.

Abstract

INTRODUCTION

Over half a million people experience homelessness on any given night in the United States. As a result of increased exposure to disease, violence, stigma, substance misuse and limited accessibility to health services, individuals experiencing homelessness are disproportionately affected by communicable diseases such as HIV and HCV with prevalence estimates as high as 21% and 36%, respectively. Pharmacists, being some of the most trusted and accessible healthcare providers, are in a unique position to have a significant impact on the nationwide initiatives in and the by offering preventative testing services and patient-centered risk mitigation counseling and education. This research looks to assess the health impacts associated with pharmacist-led HIV and HCV screening coupled with comprehensive education and risk mitigation counseling in adults experiencing homelessness.

METHODS

This study was conducted in a single independent community pharmacy in Spokane, Washington which specializes in mental health services and serves a large proportion of patients who are experiencing homelessness. Study participants are walk-in patients of the pharmacy, over the age of 18, are currently experiencing homelessness, and have not received an HIV or HCV screening within the past 6 months. The study intervention includes a Risk Determination interview, administration of HIV and HCV point-of-care antibody test, comprehensive diseases state education and personalized risk mitigation counseling. Participants are then referred to a local health clinic for confirmatory testing, anonymous partner notification, and evaluation for pre-exposure prophylaxis if indicated.

RESULTS

A total of 10 participants were included in the final data analysis. Majority of study participants were male (80%), heterosexual (90%) and over the age 30 (90%). A total of 8 participants (80%) had a reactive HCV screening and there were no reactive HIV screenings. Many of participants reported IV drug use with methamphetamine being the most used illicit substance. Half of all participants (50%) admitted to borrowing a needle for injection drug use within the past 6 months. Two participants admitted to having sexual intercourse with a partner who was known to be HCV-positive and both participants had a reactive HCV screening. All study participants reported at least one serious mental illness diagnosis and ongoing recreational drug use was cited as a coping mechanism in all participants.

CONCLUSION

Since efficacy of treatment is no longer the limiting factor in eradicating HCV and suppressing HIV viral load, public health efforts need to be refocused on patient engagement through preventative services in an environment that is less stigmatized than traditional testing sites, such as community pharmacies. Study participants were highly receptive to pharmacist-provided point-of-care screening services in the community pharmacy. Combining HIV and HCV point-of-care testing with comprehensive patient-centered education and risk mitigation counseling may result in lower rates of community transmission, improve linkage to care and may lead to long-term retention of marginalized populations such as those experiencing homelessness.

摘要

引言

在美国,任何一个夜晚都有超过50万人无家可归。由于更多地暴露于疾病、暴力、耻辱、药物滥用以及获得医疗服务的机会有限,无家可归者更容易受到诸如艾滋病毒和丙型肝炎病毒等传染病的影响,据估计,其患病率分别高达21%和36%。药剂师作为最受信任且最易接触到的医疗服务提供者,能够通过提供预防性检测服务以及以患者为中心的风险缓解咨询和教育,在全国范围内的[具体倡议1]和[具体倡议2]中发挥重大作用。本研究旨在评估由药剂师主导的艾滋病毒和丙型肝炎病毒筛查,以及为无家可归的成年人提供全面教育和风险缓解咨询所带来的健康影响。

方法

本研究在华盛顿州斯波坎市的一家独立社区药房进行,该药房专门提供心理健康服务,服务对象中有很大一部分是无家可归者。研究参与者为该药房的门诊患者,年龄在18岁以上,目前无家可归,且在过去6个月内未接受过艾滋病毒或丙型肝炎病毒筛查。研究干预措施包括风险判定访谈、艾滋病毒和丙型肝炎病毒即时检验抗体检测、全面的疾病状态教育以及个性化的风险缓解咨询。然后,参与者会被转介到当地的健康诊所进行确诊检测、匿名性伴侣通知,并在必要时进行暴露前预防评估。

结果

最终数据分析共纳入10名参与者。大多数研究参与者为男性(80%)、异性恋(90%)且年龄超过30岁(90%)。共有8名参与者(80%)丙型肝炎病毒筛查呈阳性,艾滋病毒筛查均为阴性。许多参与者报告有静脉注射吸毒史,其中甲基苯丙胺是最常使用的非法物质。所有参与者中有一半(50%)承认在过去6个月内曾借用针头用于注射毒品。两名参与者承认与已知丙型肝炎病毒呈阳性的伴侣发生过性行为,且两人丙型肝炎病毒筛查均呈阳性。所有研究参与者均报告至少被诊断出患有一种严重精神疾病,且所有参与者都将持续使用消遣性药物作为一种应对机制。

结论

由于治疗效果已不再是根除丙型肝炎病毒和抑制艾滋病毒病毒载量的限制因素,公共卫生工作需要重新聚焦于通过预防性服务让患者参与进来,所处环境要比传统检测场所(如社区药房)的污名化程度更低。研究参与者对社区药房中由药剂师提供的即时检验筛查服务高度认可。将艾滋病毒和丙型肝炎病毒即时检验与以患者为中心的全面教育和风险缓解咨询相结合,可能会降低社区传播率,改善与医疗服务的联系,并可能促使边缘化人群(如无家可归者)长期接受治疗。

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The role of community pharmacies in the HIV and HCV care continuum.社区药房在艾滋病毒和丙型肝炎护理连续过程中的作用。
Explor Res Clin Soc Pharm. 2023 Jan 11;9:100215. doi: 10.1016/j.rcsop.2022.100215. eCollection 2023 Mar.

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