Frey C, Obolensky W, Wyss H
Urol Int. 1986;41(6):444-6. doi: 10.1159/000281253.
64 out-patients suffering from recurrent UTI were treated under double-blind conditions with one capsule daily of either the biological response modifier OM-8930 or the placebo for 3 months, followed by a 3-month observation period. Dysuria, bacteriuria, leucocyturia and antibiotic or chemotherapeutic consumption showed a significant reduction under OM-8930 in comparison with the placebo. As to the tolerance, a single case of allergic exanthema on the neck was observed in the OM-8930 group. Both the curative efficacy in the acute crisis and the consolidative efficacy in preventing further recurrences showed a highly significant superior effect of OM-8930 with respect to the placebo.
64例复发性尿路感染门诊患者在双盲条件下接受治疗，每天服用一粒生物反应调节剂OM - 8930或安慰剂，为期3个月，随后是3个月的观察期。与安慰剂相比，服用OM - 8930后，尿痛、菌尿、白细胞尿以及抗生素或化疗药物的使用量均显著减少。在耐受性方面，OM - 8930组观察到1例颈部过敏性皮疹。在急性发作期的疗效以及预防进一步复发的巩固疗效方面，OM - 8930相对于安慰剂均显示出极为显著的优势。
