Carrondo Maria Cristina
Department of Clinical Physiology, Polytechnic Institute of Castelo Branco, High School of Health Dr. Lopes Dias, Castelo Branco, Portugal.
Obes Med. 2022 Jun;32:100413. doi: 10.1016/j.obmed.2022.100413. Epub 2022 Apr 22.
Type 2 diabetes mellitus is a major driver of mortality worldwide. To assess the risk factors associated with diabetes that increase in-hospital mortality.
A retrospective cohort study was conducted using the National Hospital Morbidity with a sample of 3904 diabetic women admitted (2018-2019) in public hospitals, in Portugal. The type of comorbidities and the severity of the main disease - type 2 diabetes mellitus - was assessed based on the International Classification of Diseases (ICD-9) and Disease Staging. Cox proportional hazard was used to assess mortality during hospitalization. Mortality rates and mortality risk were the main outcome measures.
In a total of 3904 diabetic women three hundred and eighty-nine (10.0%) died during hospitalization. Comorbidities bacterial pneumonia and coronary artery disease contributed 73% [Hazard ratio (HR) 1.73, 95% CI 1.32-2.27] and 37% [HR 1.37, 95% CI 1.03-1.81] respectively, to the risk of mortality, as did age over 65 years and severity 3 of the main disease.
Women with advanced type 2 diabetes mellitus, advanced age, and with comorbidities such as pneumonia and coronary artery disease admitted urgently have a higher risk of mortality during hospitalization.
2型糖尿病是全球死亡率的主要驱动因素。评估与糖尿病相关的增加住院死亡率的危险因素。
采用葡萄牙公立医院2018 - 2019年收治的3904例糖尿病女性患者样本进行回顾性队列研究。根据国际疾病分类（ICD - 9）和疾病分期评估合并症类型及主要疾病——2型糖尿病的严重程度。采用Cox比例风险模型评估住院期间的死亡率。死亡率和死亡风险是主要结局指标。
在总共3904例糖尿病女性患者中，389例（10.0%）在住院期间死亡。合并症细菌性肺炎和冠状动脉疾病分别导致73%[风险比（HR）1.73，95%置信区间1.32 - 2.27]和37%[HR 1.37，95%置信区间1.03 - 1.81]的死亡风险，65岁以上年龄和主要疾病严重程度3级也是如此。
患有晚期2型糖尿病、高龄且合并如肺炎和冠状动脉疾病等合并症并紧急入院的女性患者住院期间死亡风险更高。
