Omeke Chidimma Akudo, Enebe Joseph Tochukwu, Ugwu Ananyochukwu Innocent, Onyishi Nnaemeka Thaddeus, Omeke Moses Chukwuebuka, Enebe Nympha Onyinye, Izuka Emmanuel Obiora, Aniwada Elias Chike
Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology Teaching Hospital, Parklane, Enugu, Nigeria.
Department of Obstetrics and Gynaecology, Enugu State University of Science and Technology, College of Medicine/Teaching Hospital, Parklane, Enugu, Nigeria.
Pan Afr Med J. 2022 Feb 16;41:130. doi: 10.11604/pamj.2022.41.130.28173. eCollection 2022.
the prevalence of cervical squamous intraepithelial lesion is not well appreciated in most low-income countries. The study aimed to determine the level of awareness, prevalence and the pattern of squamous intraepithelial lesions and predictors for abnormal Pap smear reports (development of pre-malignant lesions of the cervix) among women attending various clinics in a tertiary health facility in Enugu, Nigeria.
a cross-sectional study of 207 female patients attending various clinics of Enugu State University Teaching Hospital, Parklane, Enugu between June and August 2017 was undertaken. Structured interviewer-administered questionnaires were used for data collection while cervical smears were collected from the patients and sent for cytology. Data analysis was done using the Statistical Package for the Social Sciences (SPSS) version 22.0. The results were presented as means, standard deviations, frequencies and proportions. Pearson´s Chi-square test was used to test for associations between categorical variables and statistical significance was set at a p-value of < 0.05.
the levels of awareness of cervical cancer and the screening methods among the respondents were 76.8% and 36.7% respectively. The overall knowledge of cervical cancer and its screening was poor (6.8% and 29.0% respectively). The prevalence of pre-malignant lesions of the cervix among the respondents was 15.0% with low grade squamous intraepithelial lesion (LGSIL) having the highest frequency (38.7%). Among all the other risk factors for the development of premalignant lesions of the cervix among the respondents, a report of abnormal pap (positive) smear report was significantly associated with only age ≥35 years (χ=5.723; p=0.017). The same age of 35 years and above also correctly predicted abnormal Pap smear reports among other factors (AOR = 3.02, 95% CI = 1.16 - 7.89, p = 0.024).
the awareness of cervical cancer and cervical cancer screening was high but the overall knowledge on cervical cancer and its screening was very poor among the respondents. The prevalence of pre-malignant lesions of the cervix was high, and the commonest abnormal smear was LGSIL. Only age 35 years and above correctly predicted the occurrence of abnormal Pap smear reports among the respondents.
在大多数低收入国家，宫颈鳞状上皮内病变的患病率尚未得到充分认识。本研究旨在确定尼日利亚埃努古一家三级医疗机构中，前来各诊所就诊的女性对鳞状上皮内病变的知晓程度、患病率及模式，以及巴氏涂片报告异常（宫颈癌前病变的发生）的预测因素。
对2017年6月至8月期间在埃努古州立大学教学医院帕克 lane 分院各诊所就诊的207名女性患者进行了横断面研究。采用结构化访谈问卷进行数据收集，同时从患者处采集宫颈涂片并送检进行细胞学检查。使用社会科学统计软件包（SPSS）22.0版进行数据分析。结果以均值、标准差、频率和比例表示。采用Pearson卡方检验来检验分类变量之间的关联，统计学显著性设定为p值< .05。
受访者对宫颈癌及其筛查方法的知晓率分别为76.8%和36.7%。对宫颈癌及其筛查的总体了解较差（分别为6.8%和29.0%）。受访者中宫颈上皮内瘤变的患病率为15.0%，低级别鳞状上皮内病变（LGSIL）的发生率最高（38.7%）。在受访者中所有其他宫颈癌前病变发生的危险因素中，巴氏涂片报告异常（阳性）仅与年龄≥35岁显著相关（χ=5.723；p=0.017）。35岁及以上的相同年龄在其他因素中也能正确预测巴氏涂片报告异常（优势比=3.02，95%置信区间=1.16 - 7.89，p = 0.024）。
受访者对宫颈癌和宫颈癌筛查的知晓率较高，但对宫颈癌及其筛查的总体了解非常差。宫颈上皮内瘤变的患病率较高，最常见的异常涂片是LGSIL。只有3
