吲哚烯基取代的嘧啶并[1,2 - ]吲唑类 一种简便的缩合反应。
Indoleninyl-substituted pyrimido[1,2-]indazoles a facile condensation reaction.
作者信息
Ramle Abdul Qaiyum, Fei Chee Chin, Tiekink Edward R T, Basirun Wan Jefrey
机构信息
Department of Chemistry, University of Malaya Kuala Lumpur 50603 Malaysia
Nanotechnology and Catalysis Research Centre, University of Malaya Kuala Lumpur 50603 Malaysia.
出版信息
RSC Adv. 2021 Jul 14;11(40):24647-24651. doi: 10.1039/d1ra04372b. eCollection 2021 Jul 13.
A new series of pyrimido[1,2-]indazoles bearing indolenine moieties was synthesized through a simple condensation reaction with up to 94% yield. The present method features the versatile formation of a pyrimidine ring with a broad range of substrates, great functional group compatibility and facile synthetic operation. The work offers opportunities in drug development as well as in materials science.
通过简单的缩合反应合成了一系列带有吲哚啉部分的新型嘧啶并[1,2 -]吲唑，产率高达94%。本方法的特点是能与多种底物广泛地形成嘧啶环，具有良好的官能团兼容性且合成操作简便。这项工作为药物开发以及材料科学提供了机会。
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