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采用扩大病灶内刮除术且不使用化学辅助剂治疗局部侵袭性良性骨肿瘤。

Treatment of locally aggressive benign bone tumors by means of extended intralesional curettage without chemical adjuvants.

作者信息

Yenigül Ali Erkan, Sofulu Ömer, Erol Bülent

机构信息

Department of Orthopedics and Traumatology, Faculty of Medicine, Uludağ University, Bursa, Turkey.

Department of Orthopedics and Traumatology, Marmara University Pendik Training and Research Hospital, İstanbul, Turkey.

出版信息

SAGE Open Med. 2022 Apr 22;10:20503121221094199. doi: 10.1177/20503121221094199. eCollection 2022.

Abstract

OBJECTIVES

The aim of this study is to present the clinical, oncological, and functional results of locally aggressive benign bone tumors treated with extended intralesional curettage without the use of adjuvant in a tertiary orthopedic oncology center.

METHOD

A total of 172 patients treated with surgical curettage and high-speed burrs for the diagnosis of aneurysmal bone cyst, giant cell tumor, osteoblastoma, chondroblastoma, and chondromyxoid fibroma were included in the study. Demographic, radiological, and clinical data of the patients were analyzed.

RESULTS

One-hundred seventy two patients (101 (59%) female and 71 (41%) male) with a mean age of 23 years (6-84). The mean follow-up period was 48 months (18-108). In the study, a total of 8 (4.6%) patients had postoperative complications, 17 (9.9%) patients had recurrence in the postoperative period. Diameter greater than 5 cm was found to be a risk factor for recurrence (p < 0.004). The probability of developing complications was found to be significantly higher in patients with recurrence (p < 0.001). There was no significant relationship between recurrence and age, tumor type, and tumor stage.

CONCLUSION

Successful treatment results can be obtained with extended surgical curettage, high-speed burr, and cauterization without the use of chemical adjuvants in locally aggressive bone tumors.

摘要

目的

本研究的目的是在一家三级骨科肿瘤中心,呈现采用扩大病灶内刮除术且不使用辅助剂治疗局部侵袭性良性骨肿瘤的临床、肿瘤学及功能结果。

方法

本研究纳入了总共172例接受手术刮除和高速磨钻治疗的患者,这些患者被诊断为骨动脉瘤、骨巨细胞瘤、骨母细胞瘤、软骨母细胞瘤和软骨黏液样纤维瘤。分析了患者的人口统计学、放射学和临床数据。

结果

172例患者(101例(59%)为女性,71例(41%)为男性),平均年龄23岁(6 - 84岁)。平均随访期为48个月(18 - 108个月)。在本研究中,共有8例(4.6%)患者出现术后并发症,17例(9.9%)患者在术后出现复发。发现直径大于5 cm是复发的一个危险因素(p < 0.004)。复发患者发生并发症的概率显著更高(p < 0.001)。复发与年龄、肿瘤类型和肿瘤分期之间无显著关系。

结论

对于局部侵袭性骨肿瘤,采用扩大手术刮除、高速磨钻和烧灼且不使用化学辅助剂可获得成功的治疗结果。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/e341/9036382/c2e87e056536/10.1177_20503121221094199-fig1.jpg

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