Department of Ophthalmology (YY, SP, SB, YJL), Stanford University School of Medicine, Stanford, California; Department of Ophthalmology (YY), Renji Hospital, School of Medicine, Shanghai Jiao Tong University, Shanghai, China ; and Department of Neurology (SB, YJL), Stanford University School of Medicine, Stanford, California.
J Neuroophthalmol. 2022 Jun 1;42(2):e511-e513. doi: 10.1097/WNO.0000000000001470. Epub 2022 Apr 27.
Optic disc drusen (ODD) are calcified deposits at the anterior optic nerve that are often detectable by ophthalmic imaging, including optical coherence tomography and fundus autofluorescence imaging. Multicolor (MC) imaging is a novel modality that captures reflectance of blue, green, and near-infrared laser lights with confocal scanning laser ophthalmoscopy to rapidly acquire high-resolution reflectance images of the optic disc and retina. Here, we show an eye with 3 MC imaging features of ODD, including prominent green hyperreflectance of the optic disc, green sheathing of the papillary and peripapillary vasculature (arterioles > venules), and presence of orange superficial ODD. MC imaging can provide rapid high-resolution assessment of eyes with optic nerve head elevation to help distinguish pseudopapilledema vs papilledema in children and adults without dilation, and future large studies incorporating MC imaging will help determine its contribution in the diagnosis and monitoring of ODD and assessment of other causes of optic nerve head elevation.
视盘玻璃膜疣（ODD）是视神经前部的钙化沉积物，通常可以通过眼科成像检测到，包括光学相干断层扫描和眼底自发荧光成像。多色（MC）成像技术是一种新的模式，它使用共焦扫描激光检眼镜捕捉蓝色、绿色和近红外激光光的反射，快速获取视盘和视网膜的高分辨率反射图像。在这里，我们展示了一只眼睛的 3 种 MC 成像 ODD 特征，包括视盘明显的绿色高反射、乳头和视盘周围血管（小动脉>小静脉）的绿色鞘以及橙色的浅层 ODD。MC 成像可以快速提供高分辨率的视神经头抬高评估，有助于在不扩张的情况下区分儿童和成人的假性视乳头水肿与视乳头水肿，并在未来的大型研究中纳入 MC 成像将有助于确定其在 ODD 诊断和监测以及视神经头抬高其他原因评估中的作用。
