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[三例成人脐尿管囊肿]

[Three cases of urachal cyst in adults].

作者信息

Alarcón-Molero Lorena, Martínez-Ciarpaglini Carolina, Puglia Victor, Ferrández-Izquierdo Antonio

机构信息

Servicio de Anatomía Patológica, Hospital Clínico Universitario de Valencia, Valencia, España.

Servicio de Anatomía Patológica, Hospital Clínico Universitario de Valencia, Valencia, España.

出版信息

Rev Esp Patol. 2022 Apr-Jun;55(2):135-138. doi: 10.1016/j.patol.2019.07.003. Epub 2019 Nov 10.

Abstract

The urachus is a thick fibrous cord that appears in the fifth month of pregnancy as a result of the allantois obliteration. Urachal cysts occur as a result of a defect in the obliteration of the duct, anomaly detected mainly in children and very rarely in adults. We present three cases of urachal cysts in adults, one of them detected during the study of abdominal pain and the other two, found incidentally during the study of other pathologies. In any case the possibility of urachal cysts was clinically suspected. Histologically, these lesions are lined by epithelium of urothelial type with expression of CK7, CK20, CK5/6, P63 and GATA3. The diagnosis of urachal cysts certainty lies in the histopathological study where the morphology, immunohistochemistry and a proper clinical-pathological correlation, allow to differentiate it from other more frequent abdominal cystic lesions in adults.

摘要

脐尿管是一条粗大的纤维索,在妊娠第五个月时因尿囊闭塞而出现。脐尿管囊肿是由于导管闭塞缺陷导致的,主要在儿童中检测到这种异常,在成人中非常罕见。我们报告了三例成人脐尿管囊肿病例,其中一例在腹痛检查时发现,另外两例在其他病理检查时偶然发现。在任何情况下,临床上都怀疑有脐尿管囊肿的可能性。组织学上,这些病变由尿路上皮类型的上皮细胞衬里,表达CK7、CK20、CK5/6、P63和GATA3。脐尿管囊肿的确切诊断在于组织病理学研究,通过形态学、免疫组织化学以及适当的临床病理相关性分析,能够将其与成人中其他更常见的腹部囊性病变区分开来。

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