McCowan L M, Erskine L A, Ritchie K
Am J Obstet Gynecol. 1987 Mar;156(3):655-9. doi: 10.1016/0002-9378(87)90071-8.
Umbilical artery Doppler studies were performed on the day of delivery in 15 singleton preterm pregnancies. In each case the fetus was significantly growth retarded on ultrasound examination and the attending obstetrician had made a decision to deliver the patient of the infant. Eight women had severe preeclampsia, three had mild chronic hypertension, and in four there was no recognized maternal disorder. Doppler studies were analyzed by use of the pulsatility index and the A/B ratio. In 14 of the 15 cases both were markedly abnormal. Three early neonatal deaths occurred. A positive correlation was found between the degree of abnormality of the pulsatility index and A/B ratio and a poor neonatal outcome (p less than 0.001 and p less than 0.02). Umbilical artery Doppler studies were not helpful in differentiating between intrinsic and extrinsic causes of growth retardation but seemed to identify the pregnancy at increased risk of a poor neonatal outcome.
对15例单胎早产孕妇在分娩当天进行了脐动脉多普勒检查。每例中，超声检查均显示胎儿明显生长受限，主治产科医生已决定为产妇分娩婴儿。8名妇女患有重度子痫前期，3名患有轻度慢性高血压，4名未发现母体疾病。通过使用搏动指数和A/B比值对多普勒检查结果进行分析。15例中有14例两者均明显异常。发生了3例早期新生儿死亡。发现搏动指数和A/B比值的异常程度与不良新生儿结局之间存在正相关（p<0.001和p<0.02）。脐动脉多普勒检查无助于区分生长受限的内在和外在原因，但似乎能识别出新生儿结局不良风险增加的妊娠。
