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机器人辅助根治性膀胱切除术联合佛罗伦萨机器人内置新膀胱(FloRIN):与同期开放的回肠代膀胱术(VIP)相比的功能和尿动力学特征。

Robot assisted radical cystectomy with Florence Robotic Intracorporeal Neobladder (FloRIN): Functional and urodynamic features compared with a contemporary series of open Vescica Ileale Padovana (VIP).

机构信息

Department of Experimental and Clinical Medicine, University of Florence - Unit of Oncologic Minimally-Invasive Urology and Andrology, Careggi Hospital, Florence, Italy.

Department of Experimental and Clinical Medicine, University of Florence - Unit of Oncologic Minimally-Invasive Urology and Andrology, Careggi Hospital, Florence, Italy.

出版信息

Eur J Surg Oncol. 2022 Aug;48(8):1854-1861. doi: 10.1016/j.ejso.2022.04.007. Epub 2022 Apr 20.

Abstract

INTRODUCTION

FloRIN reconfiguration technique was introduced in 2016 according to the IDEAL-Collaboration Guidelines, with the attempt to conjugate the advantages of both intracorporeal neobladder and robotic assistance. Herein we report functional outcomes of FloRIN reservoir, specifically focusing on urodynamic features.

MATERIALS AND METHODS

Consecutive patients treated with RARC and FloRIN reconstruction were prospectively collected from February 2016 to June 2020. Only patients with a minimum 6-month follow up were analyzed to obtain a stable grade of neobladder maturation before performing the urodynamic study (UDS). The FACT-BL and the QLQ-C30 EORTC questionnaires were used to evaluate urinary function and health-related QoL. Results were compared with a contemporary series of patients treated at the same Institution with open radical cystectomy (ORC) and Vescica Ileale Padovana (VIP).

RESULTS

One hundred patients entered the study and 69 patients had complete functional data. Overall, 52 (75.4%) patients reached the daytime continence. Among these, 28 (40.6%) were dry (no pads during daytime), while 24 (34.8%) used one pad/12 h. Night-time continence was achieved by 45 (65.2%) patients. Complete UDS findings were available for 28 patients. No statistically significant differences were found with the VIP-ORC group except for neobladder compliance, being higher in the FloRIN group (p = 0.03). When evaluating QoL scores, RARC with FloRIN reconfiguration showed a better continence recovery, as well as a higher improvement in urgency domain (p = 0.01), psychological status (0.02) and physical self-acceptance (p = 0.02), compared to the VIP-ORC group.

CONCLUSIONS

The FloRIN technique showed excellent functional outcomes when compared to the referral VIP-ORC procedure.

摘要

简介

FloRIN 再构技术于 2016 年根据 IDEAL-Collaboration 指南引入,旨在结合体内新膀胱和机器人辅助的优势。本文报告了 FloRIN 储尿囊的功能结果,特别是关注尿动力学特征。

材料与方法

连续接受机器人根治性膀胱切除术和 FloRIN 重建的患者,自 2016 年 2 月至 2020 年 6 月前瞻性收集。仅分析具有至少 6 个月随访的患者,以便在进行尿动力学研究(UDS)之前获得稳定的新膀胱成熟度分级。使用 FACT-BL 和 EORTC QLQ-C30 问卷评估尿功能和健康相关生活质量。结果与同一机构接受开放根治性膀胱切除术(ORC)和 Vescica Ileale Padovana(VIP)治疗的同期系列患者进行比较。

结果

100 例患者入组,69 例患者有完整的功能数据。总体而言,52 例(75.4%)患者达到日间控尿。其中,28 例(40.6%)为干性(日间无尿垫),24 例(34.8%)使用一片/12 小时。45 例(65.2%)患者达到夜间控尿。28 例患者可获得完整的 UDS 结果。除新膀胱顺应性外,与 VIP-ORC 组无统计学差异(p=0.03)。在评估生活质量评分时,与 VIP-ORC 组相比,RARC 联合 FloRIN 再构在控尿恢复方面表现更好,以及在急迫性领域(p=0.01)、心理状态(0.02)和身体自我接受(p=0.02)方面有更高的改善。

结论

与参考 VIP-ORC 手术相比,FloRIN 技术显示出优异的功能结果。

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