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ADAMTS13 conformation is closed in non-immune acquired thrombotic thrombocytopenic purpura of unidentified pathophysiology.

作者信息

Joly Bérangère S, Roose Elien, Coppo Paul, Vanhoorelbeke Karen, Veyradier Agnès

机构信息

Service d'Hématologie biologique, Hôpital Lariboisière, AP-HP.Nord, Université de Paris and EA3518, Institut Universitaire d'Hématologie, Hôpital Saint Louis, Université de Paris, Paris.

Laboratory for Thrombosis Research, IRF Life Sciences, KU Leuven Campus Kulak Kortrijk, Kortrijk.

出版信息

Haematologica. 2023 Feb 1;108(2):638-644. doi: 10.3324/haematol.2022.280768.

DOI:10.3324/haematol.2022.280768
PMID:35484652
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC9892849/
Abstract
摘要
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/811e/9892849/11a54ebcfb78/108638.fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/811e/9892849/f88c0d0dc7be/108638.fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/811e/9892849/11a54ebcfb78/108638.fig2.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/811e/9892849/f88c0d0dc7be/108638.fig1.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/811e/9892849/11a54ebcfb78/108638.fig2.jpg

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Blood Adv. 2021 Nov 9;5(21):4480-4484. doi: 10.1182/bloodadvances.2021004971.
2
Conformational plasticity of ADAMTS13 in hemostasis and autoimmunity.ADAMTS13 在止血和自身免疫中的构象可塑性。
J Biol Chem. 2021 Oct;297(4):101132. doi: 10.1016/j.jbc.2021.101132. Epub 2021 Aug 27.
3
Imbalance of von Willebrand factor and ADAMTS13 axis is rather a biomarker of strong inflammation and endothelial damage than a cause of thrombotic process in critically ill COVID-19 patients.
Arginine Methylation by PRMT1 Affects ADAMTS13 Secretion and Enzymatic Activity.PRMT1介导的精氨酸甲基化影响ADAMTS13的分泌及酶活性。
Arterioscler Thromb Vasc Biol. 2025 Apr;45(4):506-522. doi: 10.1161/ATVBAHA.124.322249. Epub 2025 Feb 13.
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The different faces of thrombotic thrombocytopenic purpura.血栓性血小板减少性紫癜的不同表现。
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Acquired thrombotic thrombocytopenic purpura without detectable anti-ADAMTS13 antibodies: a possible underlying autoimmune mechanism.获得性血栓性血小板减少性紫癜，抗ADAMTS13抗体检测不到：一种可能的潜在自身免疫机制
Haematologica. 2025 Jun 1;110(6):1368-1372. doi: 10.3324/haematol.2024.285391. Epub 2024 Sep 26.
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