• 文献检索
  • 文档翻译
  • 深度研究
  • 学术资讯
  • Suppr Zotero 插件Zotero 插件
  • 邀请有礼
  • 套餐&价格
  • 历史记录
应用&插件
Suppr Zotero 插件Zotero 插件浏览器插件Mac 客户端Windows 客户端微信小程序
定价
高级版会员购买积分包购买API积分包
服务
文献检索文档翻译深度研究API 文档MCP 服务
关于我们
关于 Suppr公司介绍联系我们用户协议隐私条款
关注我们

Suppr 超能文献

核心技术专利:CN118964589B侵权必究
粤ICP备2023148730 号-1Suppr @ 2026

文献检索

告别复杂PubMed语法,用中文像聊天一样搜索,搜遍4000万医学文献。AI智能推荐,让科研检索更轻松。

立即免费搜索

文件翻译

保留排版,准确专业,支持PDF/Word/PPT等文件格式,支持 12+语言互译。

免费翻译文档

深度研究

AI帮你快速写综述,25分钟生成高质量综述,智能提取关键信息,辅助科研写作。

立即免费体验

分析小儿吸入性损伤烧伤患者死亡的危险因素,并比较不同治疗方案的效果。

Analysis of risk factors of mortality for pediatric burned patients with inhalation injury and comparison of different treatment protocols.

机构信息

Department of Pediatric Surgery, Ankara City Hospital, Ankara-Turkey.

Department of Pediatric Surgery, Yıldırım Beyazıt University Faculty of Medicine, Ankara-Turkey.

出版信息

Ulus Travma Acil Cerrahi Derg. 2022 May;28(5):585-592. doi: 10.14744/tjtes.2021.84848.

DOI:10.14744/tjtes.2021.84848
PMID:35485476
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC10442977/
Abstract

BACKGROUND

We present our approach of pediatric burned patients with the suspicion of inhalation injury.

METHODS

This retrospective study was conducted on children with the suspicion of inhalation injury admitted to our burn center from December 2009 to December 2019. We collected data on patient demographics, total burn surface area (TBSA), presence of inhalation injury, level of carboxyhemoglobin, grade of inhalation injury, duration of mechanical ventilation, reintubation rate, total length of hospital stay, and the mortality rate. We also reviewed the required treatment of patients with inhalation injury.

RESULTS

A total of sixty pediatric burn patients were suspected inhalation injury were included in this retrospective study. 40 pa-tients included in the study were male. Age average of the patients was 87.7 months. Total burned surface area average was 32%. 46 of these patients had inhalation injury. Patients with larger cutaneous burn and needed early intubation have a higher risk of inhalation injury. There was no significant relation between inhalation injury grades and mortality and treatment protocols. Higher levels of car-boxyhemoglobin and larger TBSA are the risk factors for mortality at univariate analysis. Pediatric patient with inhalation injury whose TBSA is higher than 47.5% has a 5 times higher risk of mortality at multivariate analysis.

CONCLUSION

This study demonstrated that TBSA is the risk factor that independently affects the mortality in pediatric patients with inhalation injury. Among the patients with higher than 47.5% burn surface area, the mortality rate rises 5 times.

摘要

背景

我们提出了一种针对疑似吸入性损伤的儿科烧伤患者的处理方法。

方法

本回顾性研究纳入了 2009 年 12 月至 2019 年 12 月期间因疑似吸入性损伤而收入我院烧伤中心的儿童患者。我们收集了患者人口统计学、总烧伤面积(TBSA)、吸入性损伤的存在、碳氧血红蛋白水平、吸入性损伤程度、机械通气时间、再插管率、总住院时间和死亡率的数据。我们还回顾了吸入性损伤患者的所需治疗。

结果

本回顾性研究共纳入了 60 例疑似吸入性损伤的儿科烧伤患者。其中 40 例为男性,患者平均年龄为 87.7 个月,平均 TBSA 为 32%。46 例患者存在吸入性损伤。有较大皮肤烧伤且需要早期插管的患者,发生吸入性损伤的风险更高。吸入性损伤程度与死亡率和治疗方案之间无显著关系。单因素分析显示,较高的碳氧血红蛋白水平和较大的 TBSA 是死亡的危险因素。多因素分析显示,TBSA 高于 47.5%的吸入性损伤儿科患者的死亡率增加 5 倍。

结论

本研究表明,TBSA 是影响吸入性损伤儿科患者死亡率的独立危险因素。在烧伤面积超过 47.5%的患者中,死亡率增加 5 倍。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9147/10442977/8b6bd00eabb5/TJTES-28-585-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9147/10442977/6b21c9bcc6c9/TJTES-28-585-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9147/10442977/8b6bd00eabb5/TJTES-28-585-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9147/10442977/6b21c9bcc6c9/TJTES-28-585-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9147/10442977/8b6bd00eabb5/TJTES-28-585-g002.jpg

相似文献

1
Analysis of risk factors of mortality for pediatric burned patients with inhalation injury and comparison of different treatment protocols.分析小儿吸入性损伤烧伤患者死亡的危险因素,并比较不同治疗方案的效果。
Ulus Travma Acil Cerrahi Derg. 2022 May;28(5):585-592. doi: 10.14744/tjtes.2021.84848.
2
[Epidemiological characteristics and outcome analysis of 266 patients with inhalation injuries combined with total burn area less than 30% total body surface area].266例吸入性损伤合并烧伤总面积小于30%体表面积患者的流行病学特征及预后分析
Zhonghua Shao Shang Za Zhi. 2021 Apr 20;37(4):340-349. doi: 10.3760/cma.j.cn501120-20200229-00106.
3
Early hypothermia as risk factor in severely burned patients: A retrospective outcome study.早期低体温是严重烧伤患者的危险因素:一项回顾性结局研究。
Burns. 2019 Dec;45(8):1895-1900. doi: 10.1016/j.burns.2019.07.018. Epub 2019 Aug 2.
4
Mortality risk and length of stay associated with self-inflicted burn injury: evidence from a national sample of 30,382 adult patients.与自伤性烧伤相关的死亡风险和住院时间:来自30382名成年患者全国样本的证据。
Crit Care Med. 2008 Jan;36(1):118-25. doi: 10.1097/01.CCM.0000293122.43433.72.
5
Characteristics and outcome of burned children admitted to a pediatric intensive care unit.入住儿科重症监护病房的烧伤儿童的特征与转归
Rev Bras Ter Intensiva. 2018 Jul-Sept;30(3):333-337. doi: 10.5935/0103-507x.20180045. Epub 2018 Oct 4.
6
Microbial contamination in burn patients undergoing urgent intubation as part of their early airway management.作为早期气道管理一部分的紧急插管烧伤患者的微生物污染。
J Burn Care Res. 2008 Mar-Apr;29(2):304-10. doi: 10.1097/BCR.0b013e318166daa5.
7
The role of inhalation injury in burn trauma. A Canadian experience.吸入性损伤在烧伤创伤中的作用。加拿大的经验。
Ann Surg. 1990 Dec;212(6):720-7. doi: 10.1097/00000658-199012000-00011.
8
Massive Pediatric Burn Injury: A 10-Year Review.小儿大面积烧伤:十年回顾。
J Burn Care Res. 2023 May 2;44(3):670-674. doi: 10.1093/jbcr/irab201.
9
Impact of diagnostic bronchoscopy in burned adults with suspected inhalation injury.诊断性支气管镜检查对疑似吸入性损伤的烧伤成年患者的影响。
Burns. 2019 Sep;45(6):1275-1282. doi: 10.1016/j.burns.2019.07.011. Epub 2019 Aug 3.
10
Clinical characteristics and risk factors for severe burns complicated by early acute kidney injury.烧伤合并早期急性肾损伤的临床特点及危险因素分析。
Burns. 2020 Aug;46(5):1100-1106. doi: 10.1016/j.burns.2019.11.018. Epub 2019 Dec 13.

引用本文的文献

1
Predictors of Prolonged Hospitalization in Pediatric Burn Patients: Insights From a Rural Burn Intensive Care Unit (BICU) in Appalachia.儿科烧伤患者长期住院的预测因素:来自阿巴拉契亚农村烧伤重症监护病房(BICU)的见解
Cureus. 2025 Jan 17;17(1):e77589. doi: 10.7759/cureus.77589. eCollection 2025 Jan.
2
Knowledge level on the management of pediatric burn patients among physicians working in the emergency department.急诊医师对小儿烧伤患者管理知识的掌握程度。
Ulus Travma Acil Cerrahi Derg. 2022 Dec;29(1):73-80. doi: 10.14744/tjtes.2022.85781.

本文引用的文献

1
Indications of early intubation for patients with inhalation injury.吸入性损伤患者早期插管的指征。
Acute Med Surg. 2017 Mar 6;4(3):278-285. doi: 10.1002/ams2.269. eCollection 2017 Jul.
2
A prospective analysis of risk factors for pediatric burn mortality at a tertiary burn center in North India.印度北部一家三级烧伤中心儿童烧伤死亡率危险因素的前瞻性分析。
Burns Trauma. 2017 Sep 20;5:30. doi: 10.1186/s41038-017-0095-7. eCollection 2017.
3
Severity of Inhalation Injury is Predictive of Alterations in Gas Exchange and Worsened Clinical Outcomes.
吸入性损伤的严重程度可预测气体交换的改变及临床结局恶化。
J Burn Care Res. 2017 Nov/Dec;38(6):390-395. doi: 10.1097/BCR.0000000000000574.
4
A model of recovery from inhalation injury and cutaneous burn in ambulatory swine.非卧床猪吸入性损伤和皮肤烧伤的恢复模型。
Burns. 2017 Sep;43(6):1295-1305. doi: 10.1016/j.burns.2017.03.010. Epub 2017 Apr 12.
5
Pathophysiology, research challenges, and clinical management of smoke inhalation injury.烟雾吸入性损伤的病理生理学、研究挑战及临床管理
Lancet. 2016 Oct 1;388(10052):1437-1446. doi: 10.1016/S0140-6736(16)31458-1.
6
Does Bronchoscopic Evaluation of Inhalation Injury Severity Predict Outcome?支气管镜评估吸入性损伤严重程度能否预测预后?
J Burn Care Res. 2016 Jan-Feb;37(1):1-11. doi: 10.1097/BCR.0000000000000320.
7
Tracheostomy in pediatric burn patients.小儿烧伤患者的气管切开术。
Burns. 2015 Mar;41(2):248-51. doi: 10.1016/j.burns.2014.10.005. Epub 2014 Nov 1.
8
Inhaled anticoagulation regimens for the treatment of smoke inhalation-associated acute lung injury: a systematic review.吸入性抗凝治疗烟雾吸入相关性急性肺损伤:系统评价。
Crit Care Med. 2014 Feb;42(2):413-9. doi: 10.1097/CCM.0b013e3182a645e5.
9
Inhalation injury or mechanical ventilation: which is the true killer in burn patients?吸入性损伤还是机械通气:烧伤患者真正的致命因素是什么?
Burns. 2013 Nov;39(7):1329-30. doi: 10.1016/j.burns.2013.07.006. Epub 2013 Sep 14.
10
Burns in children: standard and new treatments.儿童烧伤:标准和新治疗方法。
Lancet. 2014 Mar 29;383(9923):1168-78. doi: 10.1016/S0140-6736(13)61093-4. Epub 2013 Sep 11.